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Preparation and characterization of novel sodium alginate/chitosan two ply composite membranes
Ma, Lihua; Yu, Weiting; Ma, Xiaojun; Ma XJ(马小军)
KeywordSodium Alginate Chitosan Composite Membrane Wound Dressing Porogen Additive
Source PublicationJOURNAL OF APPLIED POLYMER SCIENCE
2007-10-05
DOI10.1002/app.26463
Volume106Issue:1Pages:394-399
Indexed BySCI
SubtypeArticle
Department18
Funding Project1802
Contribution Rank1;1
WOS HeadingsScience & Technology ; Physical Sciences
WOS SubjectPolymer Science
WOS Research AreaPolymer Science
WOS KeywordALGINATE WOUND DRESSINGS ; IN-VITRO ; CHITOSAN ; RELEASE ; MACROPHAGES ; ACTIVATION ; CHITIN
AbstractSodium alginate/chitosan (SA/CS) two ply composite membranes were prepared by casting and solvent evaporation technique. NaHCO3 was used as a porogen additive to form pores in the interior of the composite membranes and glycerol was introduced as a plasticizer. The water uptake capacity, mechanical strength, oxygen permeation property, and in vitro cytotoxicity were evaluated to test the feasibility to utilize the composite membranes for wound dressing. The average pore size, water uptake capacity, and oxygen permeation property of the composite membranes could be adjusted by the ratio of NaHCO3 in the SA solution. The SA/CS two ply composite membranes showed high water uptake capacity, suitable mechanical strength, excellent oxygen permeability, and good biocompatible. It indicates that the SA/CS two ply composite membranes are suitable for wound dressing application. It provides a simple but promising platform to fabricate wound dressing using natural polymers. (C) 2007 Wiley Periodicals, Inc.
Language英语
URL查看原文
WOS IDWOS:000248609900052
Citation statistics
Cited Times:14[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/99053
Collection中国科学院大连化学物理研究所
Corresponding AuthorMa XJ(马小军)
Affiliation1.Chinese Acad Sci, Dalian Inst Chem Phys, Div Biotechnol, Lab Biomed Mat Engn, Dalian 116023, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
Recommended Citation
GB/T 7714
Ma, Lihua,Yu, Weiting,Ma, Xiaojun,et al. Preparation and characterization of novel sodium alginate/chitosan two ply composite membranes[J]. JOURNAL OF APPLIED POLYMER SCIENCE,2007,106(1):394-399.
APA Ma, Lihua,Yu, Weiting,Ma, Xiaojun,&马小军.(2007).Preparation and characterization of novel sodium alginate/chitosan two ply composite membranes.JOURNAL OF APPLIED POLYMER SCIENCE,106(1),394-399.
MLA Ma, Lihua,et al."Preparation and characterization of novel sodium alginate/chitosan two ply composite membranes".JOURNAL OF APPLIED POLYMER SCIENCE 106.1(2007):394-399.
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