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Identification of phenolics and nucleoside derivatives in Gastrodia elata by HPLC-UV-MS
Wang, Li; Xiao, Hongbin; Liang, Xinmiao; Wei, Lixin; Xiao HB(肖红斌); Xiao HB(肖红斌)
KeywordGastrodia Elata Lc-ms Nucleoside Phenolic
Source PublicationJOURNAL OF SEPARATION SCIENCE
2007-07-01
DOI10.1002/jssc.200600469
Volume30Issue:10Pages:1488-1495
Indexed BySCI
SubtypeArticle
Department18
Funding Project1804,1803
Contribution Rank1;1
WOS HeadingsScience & Technology ; Physical Sciences
WOS SubjectChemistry, Analytical
WOS Research AreaChemistry
WOS KeywordP-HYDROXYBENZYL ALCOHOL ; CAPILLARY-ELECTROPHORESIS ; MASS-SPECTROMETRY ; PARISHIN-B ; BLUME ; CHROMATOGRAPHY ; INHIBITION ; RHIZOMA
AbstractAn HPLC-UV-MS method for simultaneous identification of predominant phenolics and minor nucleoside derivatives in Gastrodia elata was developed, which was based on their UV and MS characteristics summarized through a series of homemade reference standard experiments. Phenolics showed characteristic UV lambda(max) at 267 nm, [M + NH4](+) base peak in positive mode and [M - H](-) base peak in negative mode while nucleosides exhibited UV lambda(max) at 255 nm, [M + H](+), [M - H + 2H(2)O](-) or [M - H + CH3COOH](-). Phenolics conjugates mainly underwent the consecutive loss of gastrodin residue (- 268 U) and the combined loss of H2O and CO2 from the citric acid unit under negative MS/MS conditions whereas nucleosides simply lost the ribose (- 132 U) under positive MS/MS conditions. According to these characteristics, a special pattern under MS/MS conditions and reported compound data for G. elata in the literature, not only 15 phenolics were identified but also 6 nucleoside derivatives were identified. Among these compounds, seven phenolics and three nucleoside derivatives have not been reported yet from G. elata.
Language英语
URL查看原文
WOS IDWOS:000248240000013
Citation statistics
Cited Times:21[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/99071
Collection中国科学院大连化学物理研究所
Corresponding AuthorXiao HB(肖红斌); Xiao HB(肖红斌)
Affiliation1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
2.Chinese Acad Sci, Res Ctr Tibetan Med, NW Plateau Inst Biol, Xining, Peoples R China
Recommended Citation
GB/T 7714
Wang, Li,Xiao, Hongbin,Liang, Xinmiao,et al. Identification of phenolics and nucleoside derivatives in Gastrodia elata by HPLC-UV-MS[J]. JOURNAL OF SEPARATION SCIENCE,2007,30(10):1488-1495.
APA Wang, Li,Xiao, Hongbin,Liang, Xinmiao,Wei, Lixin,肖红斌,&肖红斌.(2007).Identification of phenolics and nucleoside derivatives in Gastrodia elata by HPLC-UV-MS.JOURNAL OF SEPARATION SCIENCE,30(10),1488-1495.
MLA Wang, Li,et al."Identification of phenolics and nucleoside derivatives in Gastrodia elata by HPLC-UV-MS".JOURNAL OF SEPARATION SCIENCE 30.10(2007):1488-1495.
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