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题名: Effects of chitooligosaccharides on rabbit neutrophils in vitro
作者: Dou, Jiangli;  Tan, Chengyu;  Du, Yuguang;  Bai, Xuefang;  Wang, Keyi;  Ma, Xiaojun
通讯作者: 杜昱光
关键词: neurophil ;  chitooligosaccharide ;  PMA-activated
刊名: CARBOHYDRATE POLYMERS
发表日期: 2007-06-01
DOI: 10.1016/j.carbpol.2006.09.029
卷: 69, 期:2, 页:209-213
收录类别: SCI
文章类型: Article
部门归属: 18
项目归属: 1805
产权排名: 1;1
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Applied ;  Chemistry, Organic ;  Polymer Science
研究领域[WOS]: Chemistry ;  Polymer Science
英文摘要: The effects of chitooligosaccharides(COS) on resting and PMA-activated neutrophils were estimated. MTT assays, NO estimation and superoxide detection revealed that chitooligosaccharides at concentrations of 25, 50, 75, and 100 mu g/ml increased the viability, ability to produce reactive oxygen intermediates and nitrogen intermediates of resting neutrophils. Superoxide detection, degranulation assay and adhesion assay suggested that chitooligosaccharides at concentrations from 50 to 150 mu g/ml reduced PMA-induced activation of neutrophils. (C) 2006 Elsevier Ltd. All rights reserved.
关键词[WOS]: CHITOSAN ;  FLAVONOIDS ;  GENERATION ;  CANCER ;  CELLS ;  ASSAY
语种: 英语
原文出处: 查看原文
WOS记录号: WOS:000246901000001
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/99377
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
2.Chinese Acad Sci, Shanghai Inst Biochem, Shanghai 200031, Peoples R China
3.Chinese Acad Sci, Grad Sch, Beijing 100864, Peoples R China

Recommended Citation:
Dou, Jiangli,Tan, Chengyu,Du, Yuguang,et al. Effects of chitooligosaccharides on rabbit neutrophils in vitro[J]. CARBOHYDRATE POLYMERS,2007,69(2):209-213.
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