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Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu 期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 10
Authors:  Dai, Zi-Ru;  Ning, Jing;  Sun, Gui-Bo;  Wang, Ping;  Zhang, Feng;  Ma, Hong-Ping;  Zou, Li-Wei;  Hou, Jie;  Wu, Jing-Jing;  Ge, Guang-Bo;  Sun, Xiao-Bo;  Yang, Ling
Favorite  |  View/Download:7/0  |  Submit date:2019/06/20
bufotalin  cytochrome P450 3A (CYP3A)  hydroxylation  human liver microsomes (HLMs)  docking simulations  
Inhibition of human CYP3A4 and CYP3A5 enzymes by gomisin C and gomisin G, two lignan analogs derived from Schisandra chinensis 期刊论文
FITOTERAPIA, 2017, 卷号: 119, 页码: 26-31
Authors:  Zhao, Jin;  Sun, Tao;  Wu, Jing-Jing;  Cao, Yun-Feng;  Fang, Zhong-Ze;  Sun, Hong-Zhi;  Zhu, Zhi-Tu;  Yang, Kun;  Liu, Yong-Zhe;  Gonzalez, Frank J.;  Yin, Jun
Favorite  |  View/Download:46/0  |  Submit date:2017/10/29
Gomisin c  Gomisin g  Cyp3a4  Cyp3a5  Inhibition  Herb-drug Interactions  
Diethylstilbestrol can effectively accelerate estradiol-17-O-glucuronidation; while potently inhibiting estradiol-3-O-glucuronidation. 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2015, 卷号: 283, 期号: 1, 页码: 109
Authors:  Zhu LL(朱亮亮);  LingXiao;  Xia YL(夏杨柳);  KunZhou;  HuiliWang;  MinyiHuang;  Ge GB(葛广波);  YanWu;  GanlinWu;  Yang L(杨凌)
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Characterization of Phase I Metabolism of Resibufogenin and Evaluation of the Metabolic Effects on Its Antitumor Activity and Toxicity 期刊论文
DRUG METABOLISM AND DISPOSITION, 2015, 卷号: 43, 期号: 3, 页码: 299-308
Authors:  Ning, Jing;  Yu, Zhen-Long;  Hu, Liang-Hai;  Wang, Chao;  Huo, Xiao-Kui;  Deng, Sa;  Hou, Jie;  Wu, Jing-Jing;  Ge, Guang-Bo;  Ma, Xiao-Chi;  Yang, Ling
Favorite  |  View/Download:76/0  |  Submit date:2015/11/17
Interspecies variation in phase I metabolism of bufalin in hepatic microsomes from mouse, rat, dog, minipig, monkey, and human 期刊论文
XENOBIOTICA, 2015, 卷号: 45, 期号: 11, 页码: 954-960
Authors:  Ning, Jing;  Hou, Jie;  Wang, Ping;  Wu, Jing-Jing;  Dai, Zi-Ru;  Zou, Li-Wei;  Li, Wei;  Ge, Guang-Bo;  Ma, Xiao-Chi;  Yang, Ling
Favorite  |  View/Download:0/0  |  Submit date:2019/06/20
3-oxidation  5 Beta-hydroxylation  Bufalin  Cytochrome P450 3a  Species Differences  
Volatile organic metabolites identify patients with breast cancer; cyclomastopathy; and mammary gland fibroma 期刊论文
Scientific Reports, 2014, 卷号: 4, 期号: 1, 页码: 05383
Authors:  Wang ZS(王长松);  BSun;  LGuo;  XWang;  CKe;  SLiu;  WZhao;  SLuo;  ZGuo;  YZhang;  Xu GW(许国旺);  Li EY(李恩有)
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Seed-assisted synthesis of high silica ZSM-35 through interface-induced growth over MCM-49 seeds 期刊论文
MICROPOROUS AND MESOPOROUS MATERIALS, 2014, 卷号: 196, 期号: 1, 页码: 89-96
Authors:  Wang, Linying;  Tian, Peng;  Yuan, Yangyang;  Yang, Miao;  Fan, Dong;  Zhou, Hui;  Zhu, Wenliang;  Xu, Shutao;  Liu, Zhongmin;  Liu ZM(刘中民)
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High Silica Zsm-35  Mcm-49 Seeds  High Yield  Interface-induced  Dimethyl Ether Carbonylation  
Facile preparation of Sn-beta zeolites by post-synthesis (isomorphous substitution) method for isomerization of glucose to fructose 期刊论文
CHINESE JOURNAL OF CATALYSIS, 2014, 卷号: 35, 期号: 5, 页码: 723-732
Authors:  Liu, Min;  Jia, Songyan;  Li, Changzeng;  Zhang, Anfeng;  Song, Chunshan;  Guo, Xinwen
Favorite  |  View/Download:31/0  |  Submit date:2015/11/17
Sn-beta  Isomorphous Substitution  Glucose  Isomerization  Fructose  
A highly selective probe for human cytochrome P450 3A4: isoform selectivity, kinetic characterization and its applications 期刊论文
CHEMICAL COMMUNICATIONS, 2013, 卷号: 49, 期号: 84, 页码: 9779-9781
Authors:  Ge, Guang-Bo;  Ning, Jing;  Hu, Liang-Hai;  Dai, Zi-Ru;  Hou, Jie;  Cao, Yun-Feng;  Yu, Zhen-Wen;  Ai, Chun-Zhi;  Gu, Jing-Kai;  Ma, Xiao-Chi;  Yang, Ling
Favorite  |  View/Download:61/0  |  Submit date:2015/11/09
Interactions between Phytochemicals from Traditional Chinese Medicines and Human Cytochrome P450 Enzymes 期刊论文
CURRENT DRUG METABOLISM, 2012, 卷号: 13, 期号: 5, 页码: 599-614
Authors:  Wu, Jing-Jing;  Ai, Chun-Zhi;  Liu, Yong;  Zhang, Yan-Yan;  Jiang, Miao;  Fan, Xu-Ran;  Lv, Ai-Ping;  Yang, Ling;  Yang L(杨凌)
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Phytochemicals  Tcm  Cytochrome P450  Efficacy  Toxicity