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Discovery of novel antagonists on (2)-adrenoceptor from natural products using a label-free cell phenotypic assay 期刊论文
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2018, 卷号: 391, 期号: 12, 页码: 1411-1420
Authors:  Zhang, Pengyu;  Wang, Jixia;  Zhao, Ying;  Zhang, Xiuli;  Qu, Lala;  Wang, Chaoran;  Feng, Jiatao;  Wang, Anhui;  Zhou, Weijia;  Liu, Yanfang;  Hou, Tao;  Zhou, Han;  Wang, Zhiwei;  Liang, Xinmiao
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beta(2)-Adrenoceptor  Antagonist  Natural product  Label-free cell phenotypic assay  
Crotonaldehyde induces autophagy-mediated cytotoxicity in human bronchial epithelial cells via PI3K, AMPK and MAPK pathways 期刊论文
ENVIRONMENTAL POLLUTION, 2017, 卷号: 228, 页码: 287-296
Authors:  Wang, Limeng;  Li, Xiang;  Yang, Zhihua;  Pan, Xiujie;  Liu, Xingyu;  Zhu, Maoxiang;  Xie, Jianping
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Crotonaldehyde  Autophagy  Pi3k  Ampk  Mapk  
Lysophosphatidylcholines activate PPAR delta and protect human skeletal muscle cells from lipotoxicity 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2016, 卷号: 1861, 期号: 12, 页码: 1980-1992
Authors:  Klingler, Christian;  Zhao, Xinjie;  Adhikary, Till;  Li, Jia;  Xu, Guowang;  Haring, Hans-Ulrich;  Schleicher, Erwin;  Lehmann, Rainer;  Weigert, Cora
Favorite  |  View/Download:4/0  |  Submit date:2019/06/20
Lysophospholipids  Nuclear Receptors/lipid Ligands  Transcription  Skeletal Muscle  Diabetes  Human Myotubes  Ampk  
Synthesis of Chiral Piperazines via Hydrogenation of Pyrazines Activated by Alkyl Halides 期刊论文
ORGANIC LETTERS, 2016, 卷号: 18, 期号: 13, 页码: 3082-3085
Authors:  Huang, Wen-Xue;  Liu, Lian-Jin;  Wu, Bo;  Feng, Guang-Shou;  Wang, Baomin;  Zhou, Yong-Gui
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Discovery of N—methyltetrahydroprotoberberines with κ—opioid receptor agonists—opioid receptor agonist activities from corydalis yanhusuo W.T.Wang by using two—dimensional liquid chromatography 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2015, 卷号: 155, 期号: 3, 页码: 1597
Authors:  张岩;  王超然;  郭志谋;  张秀莉;  ZhiweiWang;  梁鑫淼;  OlivierCivelli
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WalPhos 配体/铑配合物对β;γ-不饱和膦酸酯的不对称催化氢化 期刊论文
应用化学, 2014, 卷号: 31, 期号: 2, 页码: 242
Authors:  段正超;  王联芝;  左晓宇;  屈桃李;  胡向平;  郑卓
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GPCR A2AAR Agonist Binding and Induced Conformation Changes of Functional Switches 期刊论文
Chinese Journal of Chemical Physics, 2014, 卷号: 27, 期号: 1, 页码: 29
Authors:  Pang XQ(庞雪芹);  Liu JY(刘建勇)
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Exploring details about structure requirements based on novel CGRP receptor antagonists urethanamide, aspartate, succinate and pyridine derivatives by in silico methods 期刊论文
JOURNAL OF MOLECULAR STRUCTURE, 2014, 卷号: 1074, 页码: 294-301
Authors:  Li, Yan;  He, Haoran;  Wang, Jinghui;  Han, Chunxiao;  Feng, Jiaqi;  Zhang, Shuwei;  Yang, Ling
Favorite  |  View/Download:37/0  |  Submit date:2015/11/17
Migraine  Cgrp Receptor Antagonist  3d-qsar  Molecular Docking  
Amide Alkaloids from Scopolia tangutica 期刊论文
PLANTA MEDICA, 2014, 卷号: 80, 期号: 13, 页码: 1124-1130
Authors:  Long, Zhen;  Zhang, Yan;  Guo, Zhimou;  Wang, Lien;  Xue, Xingya;  Zhang, Xiuli;  Wang, Shisheng;  Wang, Zhiwei;  Civelli, Olivier;  Liang, Xinmiao;  Liang XM(梁鑫淼);  Zhang XL(张秀莉)
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Scopolia Tangutica  Solanaceae  Alkaloid  Hydroxycinnamic Acid Amide  Mu-opioid Receptor  
GPCR A(2A)AR Agonist Binding and Induced Conformation Changes of Functional Switches 期刊论文
CHINESE JOURNAL OF CHEMICAL PHYSICS, 2014, 卷号: 27, 期号: 1, 页码: 29-38
Authors:  Pang, Xue-qin;  Liu, Jian-yong
Favorite  |  View/Download:24/0  |  Submit date:2015/11/17
a(2a) Adenosine Receptor  Molecular Dynamics  Adenosine  Specific Binding  Conformational Dynamics  Ionic Lock  Rotamer Toggle Switch  Secondary Structure