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The inhibition of LPS-induced inflammation in RAW264.7 macrophages via the PI3K/Akt pathway by highly N-acetylated chitooligosaccharide 期刊论文
CARBOHYDRATE POLYMERS, 2017, 卷号: 174, 页码: 1138-1143
Authors:  Xu, Qingsong;  Liu, Meisi;  Liu, Qishun;  Wang, Wenxia;  Du, Yuguang;  Yin, Heng
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N-acetylated Chitooligosaccharide  Lipopolysaccharides  Interleukin-6  Tumor Necrosis Factor-alpha  Inflammation  Pi3k/akt Pathway  
The inhibition of LPS-induced inflammation in RAW264.7 macrophages via the PI3K/Akt pathway by highly N-acetylated chitooligosaccharide 期刊论文
CARBOHYDRATE POLYMERS, 2017, 卷号: 174, 页码: 1138-1143
Authors:  Xu, Qingsong;  Liu, Meisi;  Liu, Qishun;  Wang, Wenxia;  Du, Yuguang;  Yin, Heng
Favorite  |  View/Download:17/0  |  Submit date:2017/12/19
N-acetylated Chitooligosaccharide  Lipopolysaccharides  Interleukin-6  Tumor Necrosis Factor-alpha  Inflammation  Pi3k/akt Pathway  
4 '-Hydroxywogonin suppresses lipopolysaccharide-induced inflammatory responses in RAW 264.7 macrophages and acute lung injury mice 期刊论文
PLOS ONE, 2017, 卷号: 12, 期号: 8
Authors:  Fan, Chao;  Wu, Le-Hao;  Zhang, Gu-Fang;  Xu, Fangfang;  Zhang, Shuo;  Zhang, Xiuli;  Sun, Lei;  Yu, Yang;  Zhang, Yan;  Ye, Richard D.
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Lysophosphatidylcholines activate PPAR delta and protect human skeletal muscle cells from lipotoxicity 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2016, 卷号: 1861, 期号: 12, 页码: 1980-1992
Authors:  Klingler, Christian;  Zhao, Xinjie;  Adhikary, Till;  Li, Jia;  Xu, Guowang;  Haring, Hans-Ulrich;  Schleicher, Erwin;  Lehmann, Rainer;  Weigert, Cora
Favorite  |  View/Download:4/0  |  Submit date:2019/06/20
Lysophospholipids  Nuclear Receptors/lipid Ligands  Transcription  Skeletal Muscle  Diabetes  Human Myotubes  Ampk  
Methylation, Glucuronidation, and Sulfonation of Daphnetin in Human Hepatic Preparations In Vitro: Metabolic Profiling, Pathway Comparison, and Bioactivity Analysis 期刊论文
JOURNAL OF PHARMACEUTICAL SCIENCES, 2016, 卷号: 105, 期号: 2, 页码: 808-816
Authors:  Liang, Si-Cheng;  Xia, Yang-Liu;  Hou, Jie;  Ge, Guang-Bo;  Zhang, Jiang-Wei;  He, Yu-Qi;  Wang, Jia-Yue;  Qi, Xiao-Yi;  Yang, Ling
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Daphnetin  Methylation  Glucuronidation  Sulfonation  8-o-methyldaphnetin  Anti-inflammatory Activity  
In Vitro Evaluation of the Effect of 7-Methyl Substitution on Glucuronidation of Daphnetin: Metabolic Stability, Isoform Selectivity, and Bioactivity Analysis 期刊论文
JOURNAL OF PHARMACEUTICAL SCIENCES, 2015, 卷号: 104, 期号: 10, 页码: 3557-3564
Authors:  Liang, Si-Cheng;  Ge, Guang-Bo;  Xia, Yang-Liu;  Zhang, Jiang-Wei;  Qi, Xiao-Yi;  Tu, Cai-Xia;  Yang, Ling
Favorite  |  View/Download:61/0  |  Submit date:2015/11/17
Daphnetin  Glucuronidation  Methyl Substitution  Structural Modification  Metabolic Stability  Phase Ii Enzymes  Glucuronosyltransferases  Human Liver Microsomes  Enzyme Kinetics  Metabolic Clearance  
Structural Modifications at the C-4 Position Strongly Affect the Glucuronidation of 6;7-Dihydroxycoumarins 期刊论文
DRUG METABOLISM AND DISPOSITION, 2015, 卷号: 43, 期号: 1, 页码: 553
Authors:  Xia YL(夏杨柳);  Ge GB(葛广波);  Wang P(王平);  Liang SC(梁思成);  He YQ(何芋歧);  Ning J(宁静);  Qian XK(钱星凯);  Li Y(李妍);  Yang L(杨凌)
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Insight into the Structural Determinants of Imidazole Scaffold-Based Derivatives as TNF-α Release Inhibitors by in Silico Explorations。 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2015, 卷号: 16, 期号: 1, 页码: 20118
Authors:  YuanWang;  MingweiWu;  艾纯芝;  YonghuaWang
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Drug Metabolism and Pharmacokinetic Diversity of Ranunculaceae Medicinal 期刊论文
CURRENT DRUG METABOLISM, 2015, 卷号: 16, 期号: 1, 页码: 294
Authors:  Da-ChengHao;  Ge GB(葛广波);  Pei-GenXiao;  Wang P(王平);  Yang L(杨凌)
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Interspecies variation in phase I metabolism of bufalin in hepatic microsomes from mouse; rat; dog; minipig; monkey; and human 期刊论文
XENOBIOTICA, 2015, 卷号: 45, 期号: 11, 页码: 954
Authors:  Ning J(宁静);  JieHou;  Wang P(王平);  Wu JJ(吴敬敬);  Dai ZR(戴子茹);  Zou LW(邹立伟);  WeiLi;  Ge GB(葛广波);  Xiao-ChiMa;  Yang L(杨凌)
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