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UGT1A10 Is a High Activity and Important Extrahepatic Enzyme: Why Has Its Role in Intestinal Glucuronidation Been Frequently Underestimated? 期刊论文
MOLECULAR PHARMACEUTICS, 2017, 卷号: 14, 期号: 9, 页码: 2875-2883
Authors:  Troberg, Johanna;  Jarvinen, Erkka;  Ge, Guang-Bo;  Yang, Ling;  Finel, Moshe
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Udp-glucuronosyltransferase  Recombinant Ugt1a10  Intestine Microsomes  Intestinal Glucuronidation  Estradiol  Estrone  Morphine  Sn-38  Amc  Nchn  Bavachinin  
UGT1A10 Is a High Activity and Important Extrahepatic Enzyme: Why Has Its Role in Intestinal Glucuronidation Been Frequently Underestimated? 期刊论文
MOLECULAR PHARMACEUTICS, 2017, 卷号: 14, 期号: 9, 页码: 2875-2883
Authors:  Troberg, Johanna;  Jarvinen, Erkka;  Ge, Guang-Bo;  Yang, Ling;  Finel, Moshe
Favorite  |  View/Download:24/0  |  Submit date:2017/12/20
Udp-glucuronosyltransferase  Recombinant Ugt1a10  Intestine Microsomes  Intestinal Glucuronidation  Estradiol  Estrone  Morphine  Sn-38  Amc  Nchn  Bavachinin  
Inhibition behavior of fructus psoraleae's ingredients towards human carboxylesterase 1 (hCES1) 期刊论文
XENOBIOTICA, 2016, 卷号: 46, 期号: 6, 页码: 503-510
Authors:  Sun, Dong-Xue;  Ge, Guang-Bo;  Dong, Pei-Pei;  Cao, Yun-Feng;  Fu, Zhi-Wei;  Ran, Rui-Xue;  Wu, Xue;  Zhang, Yan-Yan;  Hua, Hui-Ming;  Zhao, Zhenying;  Fang, Zhong-Ze
Favorite  |  View/Download:4/0  |  Submit date:2019/06/20
Herb-drug Interaction  Toxicity  Human Carboxylesterase 1 (Ces1)  Fructus Psoraleae  
Glucuronidation of bavachinin by human tissues and expressed UGT enzymes:Identification of UGT1A1 and UGT1A8 as the major contributing enzymes 期刊论文
Drug Metabolism and Pharmacokinetics, 2015, 卷号: 30, 期号: 0, 页码: 358
Authors:  Lv X(吕侠);  Jie Hou;  Xia YL(夏杨柳);  Ning J(宁静);  He GY(何桂元);  Wang P(王平);  Ge GB(葛广波);  Zhi-Long Xiu;  Yang L(杨凌)
Favorite  |  View/Download:37/0  |  Submit date:2016/11/24
Identification and characterization of naturally occurring inhibitors against UDP-glucuronosyltransferase 1A1 in Fructus Psoraleae (Bu-gu-zhi) 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2015, 卷号: 289, 期号: 4, 页码: 70
Authors:  Wang XX(王欣欣);  Lv X(吕侠);  Li SY(李世阳);  Hou J(侯洁);  Ning J(宁静);  Wang JY(王家悦);  Cao YF(曹云峰);  Ge GB(葛广波);  Guo B(郭斌);  Yang L(杨凌)
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Glucuronidation of bavachinin by human tissues and expressed UGT enzymes: Identification of UGT1A1 and UGT1A8 as the major contributing enzymes 期刊论文
DRUG METABOLISM AND PHARMACOKINETICS, 2015, 卷号: 30, 期号: 5, 页码: 358-365
Authors:  Lv, Xia;  Hou, Jie;  Xia, Yang-Liu;  Ning, Jing;  He, Gui-Yuan;  Wang, Ping;  Ge, Guang-Bo;  Xiu, Zhi-Long;  Yang, Ling
Favorite  |  View/Download:72/0  |  Submit date:2015/11/17
Bavachinin  Udp-glucuronosyltransferases  Ugt1a1  Ugt1a8  Glucuronidation  Human Tissues  
Fructus Psoraleae contains natural compounds with potent inhibitory effects towards human carboxylesterase 2 期刊论文
FITOTERAPIA, 2015, 卷号: 101, 期号: 1, 页码: 99-106
Authors:  Li, Yao-Guang;  Hou, Jie;  Li, Shi-Yang;  Lv, Xia;  Ning, Jing;  Wang, Ping;  Liu, Zhao-Ming;  Ge, Guang-Bo;  Ren, Jia-Yan;  Yang, Ling;  Ge GB(葛广波);  Jia-YanRen;  Yang L(杨凌)
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Fructus Psoraleae  Human Carboxylesterase 2  Inhibitory Effects  Lc-dad-esi-ms/ms  
UDP-GLUCURONOSYLTRANSFERASE 1A1 IS THE PRINCIPAL ENZYME RESPONSIBLE FOR BAVACHININ GLUCURONIDATION IN HUMAN LIVER MICROSOMES 期刊论文
DRUG METABOLISM REVIEWS, 2014, 卷号: 45, 页码: 65-65
Authors:  Lv, Xia;  Ge, Guang-Bo;  Ning, Jing;  Hou, Jie;  Yang, Ling;  Ma, Xiao-Chi
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UDP-glucuronosyltransferase 1A1 is the principal enzyme responsible for Bavachinin glucuronidation in human liver microsomes 会议论文
, 多伦多, 41546
Authors:  Lv X(吕霞);  Ge GB(葛广波);  Ning J(宁静);  Hou J(侯洁);  Yang L(杨凌);  Ma XC(马骁驰)
Favorite  |  View/Download:142/0  |  Submit date:2014/09/11