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EGFR signaling confers resistance to BET inhibition in hepatocellular carcinoma through stabilizing oncogenic MYC 期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2019, 卷号: 38, 页码: 15
Authors:  Yin, Yalei;  Sun, Mingju;  Zhan, Xi;  Wu, Changqing;  Geng, Pengyu;  Sun, Xiaoyan;  Wu, Yunsong;  Zhang, Shuijun;  Qin, Jianhua;  Zhuang, Zhengping;  Liu, Yang
Favorite  |  View/Download:5/0  |  Submit date:2019/06/20
Bromodomain  JQ1  MAPK pathway  MYC  EGFR mutation  Sorafenib  
Y08060: A Selective BET Inhibitor for Treatment of Prostate Cancer 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 3, 页码: 262-267
Authors:  Xiang, Quping;  Zhang, Yan;  Li, Jiaguo;  Xue, Xiaoqian;  Wang, Chao;  Song, Ming;  Zhang, Cheng;  Wang, Rui;  Li, Chenchang;  Wu, Chun;  Zhou, Yulai;  Yang, Xiaohong;  Li, Guohui;  Ding, Ke;  Xu, Yong
Favorite  |  View/Download:6/0  |  Submit date:2019/06/20
Bromodomain  Brd4  Prostate Cancer  Epigenetics  
Molecular Dynamic Simulation Insights into the Normal State and Restoration of p53 Function 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2012, 卷号: 13, 期号: 8, 页码: 9709-9740
Authors:  Fu, Ting;  Min, Hanyi;  Xu, Yong;  Chen, Jianzhong;  Li, Guohui;  Li GH(李国辉)
Adobe PDF(624Kb)  |  Favorite  |  View/Download:111/34  |  Submit date:2013/10/11
P53  Mdm2  Mdmx  Molecular Dynamic Simulation  Conformational Change  Protein-protein Interaction  Protein-ligand Interaction