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Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu 期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 10
Authors:  Dai, Zi-Ru;  Ning, Jing;  Sun, Gui-Bo;  Wang, Ping;  Zhang, Feng;  Ma, Hong-Ping;  Zou, Li-Wei;  Hou, Jie;  Wu, Jing-Jing;  Ge, Guang-Bo;  Sun, Xiao-Bo;  Yang, Ling
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bufotalin  cytochrome P450 3A (CYP3A)  hydroxylation  human liver microsomes (HLMs)  docking simulations  
Separation and characterization of bufadienolides in toad skin using two-dimensional normal-phase liquid chromatography x reversed-phase liquid chromatography coupled with mass spectrometry 期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2016, 卷号: 1026, 页码: 67-74
Authors:  Zhang, Yun;  Jin, Hongli;  Li, Xiaolong;  Zhao, Jianqiang;  Guo, Xiujie;  Wang, Jixia;  Guo, Zhimou;  Zhang, Xiuli;  Tao, Yanduo;  Liu, Yanfang;  Chen, Deliang;  Liang, Xinmiao
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Bufadienolides  Normal-phase Liquid Chromatography  Two-dimensional Liquid Chromatography  Ms/ms  Toad Skin  
Anti-gastric cancer activity in three-dimensional tumor spheroids of bufadienolides 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6
Authors:  Wang, Jixia;  Zhang, Xiuli;  Li, Xiaolong;  Zhang, Yun;  Hou, Tao;  Wei, Lai;  Qu, Lala;  Shi, Liying;  Liu, Yanfang;  Zou, Lijuan;  Liang, Xinmiao
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Characterization of regio- and stereo-selective sulfation of bufadienolides: exploring the mechanism and providing insight into the structure-sulfation relationship by experimentation and molecular docking analysis 期刊论文
RSC ADVANCES, 2016, 卷号: 6, 期号: 7, 页码: 5774-5783
Authors:  Ning, Jing;  Cui, Yonglei;  Wang, Chao;  Dong, Peipei;  Ge, Guangbo;  Tian, Xiangge;  Hou, Jie;  Huo, Xiaokui;  Zhang, Baojing;  Ma, Tonghui;  Ma, Xiaochi
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A highly selective probe for UDPglucuronosyltransferase2B7 (UGT2B7) in human microsomes: isoform specificity; kinetic characterization; and applications. 期刊论文
RSC Advances, 2015, 卷号: 5, 期号: 1, 页码: 5924
Authors:  Xiang-GeTian;  ChaoWang;  Ge GB(葛广波);  Ning J(宁静);  Ai CZ(艾纯芝);  JamesY.Hong;  Yong-XvCai;  Xiao-KuiHuo;  JieHou;  Ke-XinLiu;  Hong-ZhiSun;  Xiao-ChiMa
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Interspecies variation in phase I metabolism of bufalin in hepatic microsomes from mouse; rat; dog; minipig; monkey; and human 期刊论文
XENOBIOTICA, 2015, 卷号: 45, 期号: 11, 页码: 954
Authors:  Ning J(宁静);  JieHou;  Wang P(王平);  Wu JJ(吴敬敬);  Dai ZR(戴子茹);  Zou LW(邹立伟);  WeiLi;  Ge GB(葛广波);  Xiao-ChiMa;  Yang L(杨凌)
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psi-Bufarenogin, a novel anti-tumor compound, suppresses liver cancer growth by inhibiting receptor tyrosine kinase-mediated signaling 期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 13, 页码: 11627-11639
Authors:  Ding, Jin;  Wen, Wen;  Xiang, Daimin;  Yin, Peipei;  Liu, Yanfang;  Liu, Chang;  He, Guoping;  Cheng, Zhuo;  Yin, Jianpeng;  Sheng, Chunquan;  Zhang, Wen;  Nan, Fajun;  Ye, Wencai;  Zhang, Xiuli;  Wang, Hongyang
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Psi-bufarenogin  Hepatocellular Carcinoma  Epithelial Growth Factor Receptor  Hepatocyte Growth Factor Receptor  
Characterization of Phase I Metabolism of Resibufogenin and Evaluation of the Metabolic Effects on Its Antitumor Activity and Toxicity 期刊论文
DRUG METABOLISM AND DISPOSITION, 2015, 卷号: 43, 期号: 3, 页码: 299-308
Authors:  Ning, Jing;  Yu, Zhen-Long;  Hu, Liang-Hai;  Wang, Chao;  Huo, Xiao-Kui;  Deng, Sa;  Hou, Jie;  Wu, Jing-Jing;  Ge, Guang-Bo;  Ma, Xiao-Chi;  Yang, Ling
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Pharmacokinetics and tissue distribution of five bufadienolides from the Shexiang Baoxin pill following oral administration to mice 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2015, 卷号: 161, 页码: 175-185
Authors:  Huang, Huimei;  Yang, Yongge;  Lv, Chao;  Chang, Wanlin;  Peng, Chengcheng;  Wang, Shuping;  Ge, Guangbo;  Han, Lin;  Zhang, Weidong;  Liu, Runhui
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Bufadienolides  Shexiang Baoxin Pill  Pharmacokinetic  Tissue Distribution  Lc-esi-ms/ms  
Preparative separation of a challenging anthocyanin from Lycium ruthenicum Murr. by two-dimensional reversed-phase liquid chromatography/hydrophilic interaction chromatography 期刊论文
RSC ADVANCES, 2015, 卷号: 5, 期号: 76, 页码: 62134-62141
Authors:  Jin, Hongli;  Zhao, Jianqiang;  Zhou, Weijia;  Shen, Aijin;  Yang, Fan;  Liu, Yanfang;  Guo, Zhimou;  Zhang, Xiuli;  Tao, Yanduo;  Peng, Xiaojun;  Liang, Xinmiao
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