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Short-chain chlorinated paraffins (SCCPs) disrupt hepatic fatty acid metabolism in liver of male rat via interacting with peroxisome proliferator-activated receptor a (PPAR alpha) 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 181, 页码: 164-171
Authors:  Gong, Yufeng;  Zhang, Haijun;  Geng, Ningbo;  Ren, Xiaoqian;  Giesy, John P.;  Luo, Yun;  Xing, Liguo;  Wu, Ping;  Yu, Zhengkun;  Chen, Jiping
Favorite  |  View/Download:16/0  |  Submit date:2019/12/02
SCCPs  Mode of action  PPAR alpha  Luciferase assay  Molecular docking  Metabolomics  
Dual-Functional Titanium(IV) Immobilized Metal Affinity Chromatography Approach for Enabling Large-Scale Profiling of Protein Mannose-6-Phosphate Glycosylation and Revealing Its Predominant Substrates 期刊论文
ANALYTICAL CHEMISTRY, 2019, 卷号: 91, 期号: 18, 页码: 11589-11597
Authors:  Huang, Junfeng;  Dong, Jing;  Shi, Xudong;  Chen, Zhengwei;  Cui, Yusi;  Liu, Xiaoyan;  Ye, Mingliang;  Li, Lingjun
Favorite  |  View/Download:13/0  |  Submit date:2019/12/02
Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK 期刊论文
CELL METABOLISM, 2019, 卷号: 30, 期号: 3, 页码: 508-+
Authors:  Li, Mengqi;  Zhang, Chen-Song;  Zong, Yue;  Feng, Jin-Wei;  Ma, Teng;  Hu, Meiqin;  Lin, Zhizhong;  Li, Xiaotong;  Xie, Changchuan;  Wu, Yaying;  Jiang, Dong;  Li, Ying;  Zhang, Cixiong;  Tian, Xiao;  Wang, Wen;  Yang, Yanyan;  Chen, Jie;  Cui, Jiwen;  Wu, Yu-Qing;  Chen, Xin;  Liu, Qing-Feng;  Wu, Jianfeng;  Lin, Shu-Yong;  Ye, Zhiyun;  Liu, Ying;  Piao, Hai-Long;  Yu, Li;  Zhou, Zhuan;  Xie, Xiao-Song;  Hardie, D. Grahame;  Lin, Sheng-Cai
Favorite  |  View/Download:12/0  |  Submit date:2019/12/02
Saxagliptin alters bile acid profiles and yields metabolic benefits in drug-naive overweight or obese type 2 diabetes patient 期刊论文
JOURNAL OF DIABETES, 2019, 页码: 11
Authors:  Li, Wen;  Liu, Ruixin;  Li, Xuelin;  Tao, Bei;  Zhai, Nan;  Wang, Xiaolin;  Li, Qi;  Zhang, Yifei;  Gu, Weiqiong;  Wang, Weiqing;  Ning, Guang
Favorite  |  View/Download:12/0  |  Submit date:2019/12/02
bile acids  dipeptidyl peptidase-4 inhibitor  obesity  saxagliptin  type 2 diabetes  
Discovery of novel antagonists on (2)-adrenoceptor from natural products using a label-free cell phenotypic assay 期刊论文
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2018, 卷号: 391, 期号: 12, 页码: 1411-1420
Authors:  Zhang, Pengyu;  Wang, Jixia;  Zhao, Ying;  Zhang, Xiuli;  Qu, Lala;  Wang, Chaoran;  Feng, Jiatao;  Wang, Anhui;  Zhou, Weijia;  Liu, Yanfang;  Hou, Tao;  Zhou, Han;  Wang, Zhiwei;  Liang, Xinmiao
Favorite  |  View/Download:22/0  |  Submit date:2019/06/20
beta(2)-Adrenoceptor  Antagonist  Natural product  Label-free cell phenotypic assay  
Saikosaponin D from Radix Bupleuri suppresses triple-negative breast cancer cell growth by targeting beta-catenin signaling 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2018, 卷号: 108, 页码: 724-733
Authors:  Wang, Jixia;  Qi, Huan;  Zhang, Xiuli;  Si, Wei;  Xu, Fangfang;  Hou, Tao;  Zhou, Han;  Wang, Anhui;  Li, Guohui;  Liu, Yanfang;  Fang, Ye;  Piao, Hai-long;  Liang, Xinmiao
Favorite  |  View/Download:19/0  |  Submit date:2019/06/20
Triple-negative breast cancer  Saikosaponin D  Radix Bupleuri  Wnt/beta-catenin  
Identification of Alkaloids from Corydalis yanhusuo W. T. Wang as Dopamine D-1 Receptor Antagonists by Using CRE-Luciferase Reporter Gene Assay 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 10, 页码: 10
Authors:  Wu, Lehao;  Zhang, Weiyue;  Qiu, Xin;  Wang, Chaoran;  Liu, Yanfang;  Wang, Zhiwei;  Yu, Yang;  Ye, Richard D.;  Zhang, Yan
Favorite  |  View/Download:24/0  |  Submit date:2019/06/20
Corydalis yanhusuoW. T. Wang  luciferase reporter gene assay  D-1 receptor  FLIPR  
A Hydrogenation/Oxidative Fragmentation Cascade for Synthesis of Chiral 4,5-Dihydro-1H-benzo[d]azepin-1-ones 期刊论文
ORGANIC LETTERS, 2016, 卷号: 18, 期号: 22, 页码: 5920-5923
Authors:  Shen, Hong-Qiang;  Gao, Xiang;  Liu, Cong;  Hu, Shu-Bo;  Zhou, Yong-Gui
Favorite  |  View/Download:11/0  |  Submit date:2019/06/20
Mesenchymal stem cells enhance the metastasis of 3D-cultured hepatocellular carcinoma cells 期刊论文
BMC Cancer, 2016, 卷号: 16, 期号: 1
Authors:  Liu,Chang;  Liu,Yang;  Xu,Xiao-xi;  Guo,Xin;  Sun,Guang-wei;  Ma,Xiao-jun
Favorite  |  View/Download:11/0  |  Submit date:2019/06/20
Three-dimensional cell culture  Umbilical cord mensenchymal stem cells  Hepatocellular carcinoma  Metastasis  TGF-β  
Computational Analysis of Structure-Based Interactions for Novel H-1-Antihistamines 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2016, 卷号: 17, 期号: 1
Authors:  Yang, Yinfeng;  Li, Yan;  Pan, Yanqiu;  Wang, Jinghui;  Lin, Feng;  Wang, Chao;  Zhang, Shuwei;  Yang, Ling
Favorite  |  View/Download:7/0  |  Submit date:2019/06/20
3d-qsar  H-1-antihistamines  Docking  Molecular Dynamics