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Inhibitory effects of tanshinones towards the catalytic activity of UDP-glucuronosyltransferases (UGTs) 期刊论文
PHARMACEUTICAL BIOLOGY, 2017, 卷号: 55, 期号: 1, 页码: 1703-1709
Authors:  Zhang, Xu-Xin;  Cao, Yun-Feng;  Wang, Li-Xuan;  Yuan, Xiao-Lin;  Fang, Zhong-Ze
Favorite  |  View/Download:29/0  |  Submit date:2017/10/29
Enzyme Inhibition  Herb-drug Interaction  In Vitro screenIng  In vitro-In Vivo Extrapolation (Iv-ive)  
Cytochrome P450 promiscuity leads to a bifurcating biosynthetic pathway for tanshinones 期刊论文
NEW PHYTOLOGIST, 2016, 卷号: 210, 期号: 2, 页码: 525-534
Authors:  Guo, Juan;  Ma, Xiaohui;  Cai, Yuan;  Ma, Ying;  Zhan, Zhilai;  Zhou, Yongjin J.;  Liu, Wujun;  Guan, Mengxin;  Yang, Jian;  Cui, Guanghong;  Kang, Liping;  Yang, Lei;  Shen, Ye;  Tang, Jinfu;  Lin, Huixin;  Ma, Xiaojing;  Jin, Baolong;  Liu, Zhenming;  Peters, Reuben J.;  Zhao, Zongbao K.;  Huang, Luqi
Favorite  |  View/Download:1/0  |  Submit date:2019/06/20
Cytochrome P450 (Cyp) Monooxygenases  Diterpenoid Biosynthesis  Enzymatic Promiscuity  Metabolic Pathways  Salvia Miltiorrhiza Bunge  Synthetic Biology  
Discovery of new targets of phenolic acids in Danshen using label-free cell phenotypic assay 期刊论文
RSC Advances, 2016, 卷号: 5, 期号: 0, 页码: 25768
Authors:  Wang JX(王纪霞);  Hou T(侯滔);  Wei L(魏来);  Shi LY(史丽颖);  He J(何牮);  Nan Zhou;  Sun GW(孙广炜);  Zhang XL(张秀莉);  Liang XM(梁鑫淼)
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Double Off-line Two-dimensional Liquid Chromatography for Separation and Identification of Compounds in Salvia Miltiorrhiza (Danshen) 期刊论文
世界中医药, 2015, 卷号: 1, 期号: 3, 页码: 27
Authors:  Wang JX(王纪霞);  Zhang XL(张秀莉);  Yang F(杨帆);  Jin HL(金红利);  Shi LY(史丽颖);  Zhou WJ(周维佳);  Liu YF(刘艳芳);  Liang XM(梁鑫淼)
Favorite  |  View/Download:31/0  |  Submit date:2016/11/24
Discovery of new targets of phenolic acids in danshen using a label-free cell phenotypic assay 期刊论文
RSC ADVANCES, 2015, 卷号: 5, 期号: 33, 页码: 25768-25776
Authors:  Wang, Jixia;  Hou, Tao;  Wei, Lai;  Shi, Liying;  He, Jian;  Zhou, Nan;  Sun, Guangwei;  Zhang, Xiuli;  Liang, Xinmiao
Favorite  |  View/Download:62/0  |  Submit date:2015/11/17
Metabolomics and traditional Chinese medicine 期刊论文
TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2014, 卷号: 61, 期号: 1, 页码: 207-214
Authors:  Hu, Chunxiu;  Xu, Guowang;  Xu GW(许国旺)
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Analytical Characterization  Bioactive Component  Biochemistry  Chinese Herbal Medicine  Chromatographic Fingerprinting  Holistic Bioactivity  Metabolomics  Multi-component Mixture  Tcm Syndrome  Traditional Chinese Medicine  
Combining metabolomics and transcriptomics to characterize tanshinone biosynthesis in Salvia miltiorrhiza 期刊论文
BMC GENOMICS, 2014, 卷号: 15, 期号: 73, 页码: 1
Authors:  Gao, Wei;  Sun, Hai-Xi;  Xiao, Hongbin;  Cui, Guanghong;  Hillwig, Matthew L.;  Jackson, Alana;  Wang, Xiao;  Shen, Ye;  Zhao, Nan;  Zhang, Liangxiao;  Wang, Xiu-Jie;  Peters, Reuben J.;  Huang, Luqi;  Xiu-Jie Wang;  Reuben J Peters;  Luqi Huang
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Systems pharmacology strategies for drug discovery and combination with applications to cardiovascular diseases 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2014, 卷号: 151, 期号: 1, 页码: 93-107
Authors:  Li, Peng;  Chen, Jianxin;  Wang, Jinan;  Zhou, Wei;  Wang, Xia;  Li, Bohui;  Tao, Weiyang;  Wang, Wei;  Wang, Yonghua;  Yang, Ling
Favorite  |  View/Download:21/0  |  Submit date:2015/11/17
Cardiovascular Diseases  Drug Discovery And Combination  Systems Pharmacology  Systems Biology  
Label-free cell phenotypic profiling identifies pharmacologically active compounds in two traditional Chinese medicinal plants 期刊论文
RSC ADVANCES, 2014, 卷号: 4, 期号: 50, 页码: 26368-26377
Authors:  Zhang, Xiuli;  Deng, Huayun;  Xiao, Yuansheng;  Xue, Xingya;  Ferrie, Ann M.;  Elizabeth Tran;  Liang, Xinmiao;  Fang, Ye;  Liang XM(梁鑫淼);  Ye Fang
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CYP76AH1 catalyzes turnover of miltiradiene in tanshinones biosynthesis and enables heterologous production of ferruginol in yeasts 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2013, 卷号: 110, 期号: 29, 页码: 12108-12113
Authors:  Guo, Juan;  Zhou, Yongjin J.;  Hillwigc, Matthew L.;  Shen, Ye;  Yang, Lei;  Wang, Yajun;  Zhang, Xianan;  Liu, Wujun;  Peters, Reuben J.;  Chen, Xiaoya;  Zhao, Zongbao K.;  Huang, Luqi;  Zhao ZB(赵宗保);  Peters RJ;  Huang LQ(黄璐琦)
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Phytoterpenoids Biosynthesis  Gene Discovery  Synthetic Pathway  Metabolic Engineering