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UDP-glucose accelerates SNAI1 mRNA decay and impairs lung cancer metastasis 期刊论文
NATURE, 2019, 卷号: 571, 期号: 7763, 页码: 127-+
Authors:  Wang, Xiongjun;  Liu, Ruilong;  Zhu, Wencheng;  Chu, Huiying;  Yu, Hua;  Wei, Ping;  Wu, Xueyuan;  Zhu, Hongwen;  Gao, Hong;  Liang, Ji;  Li, Guohui;  Yang, Weiwei
Favorite  |  View/Download:3/0  |  Submit date:2019/12/02
Recent progress and challenges in screening and characterization of UGT1A1 inhibitors 期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 2, 页码: 258-278
Authors:  Lv, Xia;  Xia, Yangliu;  Finel, Moshe;  Wu, Jingjing;  Ge, Guangbo;  Yang, Ling
Favorite  |  View/Download:3/0  |  Submit date:2019/06/20
UGT1A1 inhibitors  Drug/herbdrug interactions  Probe substrates  High-throughput screening  
Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu 期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 10
Authors:  Dai, Zi-Ru;  Ning, Jing;  Sun, Gui-Bo;  Wang, Ping;  Zhang, Feng;  Ma, Hong-Ping;  Zou, Li-Wei;  Hou, Jie;  Wu, Jing-Jing;  Ge, Guang-Bo;  Sun, Xiao-Bo;  Yang, Ling
Favorite  |  View/Download:10/0  |  Submit date:2019/06/20
bufotalin  cytochrome P450 3A (CYP3A)  hydroxylation  human liver microsomes (HLMs)  docking simulations  
recentprogressandchallengesinscreeningandcharacterizationofugt1a1inhibitors 期刊论文
actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 2, 页码: 258
Authors:  Lv Xia;  Xia Yangliu;  Finel Moshe;  Wu Jingjing;  Ge Guangbo;  Yang Ling
Favorite  |  View/Download:1/0  |  Submit date:2019/12/02
A Practical and High-Affinity Fluorescent Probe for Uridine Diphosphate Glucuronosyltransferase 1A1: A Good Surrogate for Bilirubin 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 23, 页码: 9664-9675
Authors:  Lv, Xia;  Feng, Lei;  Ai, Chun-Zhi;  Hou, Jie;  Wang, Ping;  Zou, Li-Wei;  Cheng, Jie;  Ge, Guang-Bo;  Cui, Jing-Nan;  Yang, Ling
Favorite  |  View/Download:6/0  |  Submit date:2019/06/20
Bioactivity-Guided Fractionation of Pine Needle Reveals Catechin as an Anti-hypertension Agent via Inhibiting Angiotensin-Converting Enzyme 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7
Authors:  He, Jian
Favorite  |  View/Download:10/0  |  Submit date:2017/12/19
Bioactivity-Guided Fractionation of Pine Needle Reveals Catechin as an Anti-hypertension Agent via Inhibiting Angiotensin-Converting Enzyme 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7
Authors:  He, Jian
Favorite  |  View/Download:12/0  |  Submit date:2017/12/19
A Naturally Occurring Isoform-Specific Probe for Highly Selective and Sensitive Detection of Human Cytochrome P450 3A5 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 页码: 3804-3813
Authors:  Wu, Jing-Jing;  Cao, Yun-Feng;  Feng, Liang;  He, Yu-Qi;  Hong, James Y.;  Dou, Tong-Yi;  Wang, Ping;  Hao, Da-Cheng;  Ge, Guang-Bo;  Yang, Ling
Favorite  |  View/Download:47/0  |  Submit date:2017/10/29
A highly specific ratiometric two-photon fluorescent probe to detect dipeptidyl peptidase IV in plasma and living systems 期刊论文
BIOSENSORS & BIOELECTRONICS, 2017, 卷号: 90, 页码: 283-289
Authors:  Zou, Li-Wei;  Wang, Ping;  Qian, Xing-Kai;  Feng, Lei;  Yu, Yang;  Wang, Dan-Dan;  Jin, Qiang;  Hou, Jie;  Liu, Zhi-Hong;  Ge, Guang-Bo;  Yang, Ling
Favorite  |  View/Download:45/0  |  Submit date:2017/10/29
Dipeptidyl Peptidase Iv  Two-photon Fluorescent Probe  Cells And Tissues Imaging  Inhibitor Screening  
MYC-driven inhibition of the glutamate-cysteine ligase promotes glutathione depletion in liver cancer 期刊论文
EMBO REPORTS, 2017, 卷号: 18, 页码: 569-585
Authors:  Anderton, Brittany;  Camarda, Roman;  Balakrishnan, Sanjeev;  Balakrishnan, Asha;  Kohnz, Rebecca A.;  Lim, Lionel;  Evason, Kimberley J.;  Momcilovic, Olga;  Kruttwig, Klaus;  Huang, Qiang;  Xu, Guowang;  Nomura, Daniel K.;  Goga, Andrei
Favorite  |  View/Download:20/0  |  Submit date:2017/10/29
Cancer  Glutathione  Metabolism  Mirna  Myc