DICP OpenIR

Browse/Search Results:  1-10 of 137 Help

Selected(0)Clear Items/Page:    Sort:
Therapeutic effect and autophagy regulation of myriocin in nonalcoholic steatohepatitis 期刊论文
LIPIDS IN HEALTH AND DISEASE, 2019, 卷号: 18, 期号: 1, 页码: 11
Authors:  Yang, Rui-Xu;  Pan, Qin;  Liu, Xiao-Lin;  Zhou, Da;  Xin, Feng-Zhi;  Zhao, Ze-Hua;  Zhang, Rui-Nan;  Zeng, Jing;  Qiao, Liang;  Hu, Chun-Xiu;  Xu, Guo-Wang;  Fan, Jian-Gao
Favorite  |  View/Download:2/0  |  Submit date:2019/12/02
Ceramides  Autophagy  High fat diet  Non-alcoholic fatty liver disease  
Short-chain chlorinated paraffins (SCCPs) disrupt hepatic fatty acid metabolism in liver of male rat via interacting with peroxisome proliferator-activated receptor a (PPAR alpha) 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 181, 页码: 164-171
Authors:  Gong, Yufeng;  Zhang, Haijun;  Geng, Ningbo;  Ren, Xiaoqian;  Giesy, John P.;  Luo, Yun;  Xing, Liguo;  Wu, Ping;  Yu, Zhengkun;  Chen, Jiping
Favorite  |  View/Download:2/0  |  Submit date:2019/12/02
SCCPs  Mode of action  PPAR alpha  Luciferase assay  Molecular docking  Metabolomics  
Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu 期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 10
Authors:  Dai, Zi-Ru;  Ning, Jing;  Sun, Gui-Bo;  Wang, Ping;  Zhang, Feng;  Ma, Hong-Ping;  Zou, Li-Wei;  Hou, Jie;  Wu, Jing-Jing;  Ge, Guang-Bo;  Sun, Xiao-Bo;  Yang, Ling
Favorite  |  View/Download:10/0  |  Submit date:2019/06/20
bufotalin  cytochrome P450 3A (CYP3A)  hydroxylation  human liver microsomes (HLMs)  docking simulations  
Short-chain chlorinated paraffins (SCCPs) induced thyroid disruption by enhancement of hepatic thyroid hormone influx and degradation in male Sprague Dawley rats 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2018, 卷号: 625, 页码: 657-666
Authors:  Gong, Yufeng;  Zhang, Haijun;  Geng, Ningbo;  Xing, Liguo;  Fan, Jingfeng;  Luo, Yun;  Song, Xiaoyao;  Ren, Xiaoqian;  Wang, Feidi;  Chen, Jiping
Favorite  |  View/Download:8/0  |  Submit date:2019/06/20
Short-chain Chlorinated Paraffins  Thyroid Disruption  Hepatic Metabolism  Thyroid Hormone  Constitutive Androstane Receptor  
New Insights into SN-38 Glucuronidation: Evidence for the Important Role of UDP Glucuronosyltransferase 1A9 期刊论文
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2018, 卷号: 122, 期号: 4, 页码: 424-428
Authors:  Xiao, Ling;  Zhu, Liangliang;  Li, Wenjuan;  Li, Conghu;  Cao, Yunfeng;  Ge, Guangbo;  Sun, Xiaoyu
Favorite  |  View/Download:4/0  |  Submit date:2019/06/20
Assessment of hepatic metabolism-dependent nephrotoxicity on an organs-on-a-chip microdevice 期刊论文
TOXICOLOGY IN VITRO, 2018, 卷号: 46, 页码: 1-8
Authors:  Li, Zhongyu;  Jiang, Lei;  Zhu, Yujuan;  Su, Wentao;  Xu, Cong;  Tao, Tingting;  Shi, Yang;  Qin, Jianhua
Favorite  |  View/Download:4/0  |  Submit date:2019/06/20
Microfluidics  Drug Testing  Hepatic Metabolism  Nephrotoxicity  Organs-on-a-chip  
Paper supported long-term 3D liver co-culture model for the assessment of hepatotoxic drugs 期刊论文
TOXICOLOGY RESEARCH, 2018, 卷号: 7, 期号: 1, 页码: 13-21
Authors:  Wang, Yaqing;  Su, Wentao;  Wang, Li;  Jiang, Lei;  Liu, Yang;  Hui, Lijian;  Qin, Jianhua
Favorite  |  View/Download:2/0  |  Submit date:2019/06/20
High-throughput metabolic profiling based on small amount of hepatic cells 期刊论文
ELECTROPHORESIS, 2017, 卷号: 38, 期号: 18, 页码: 2296-2303
Authors:  Zhou, Lina;  Yin, Peiyuan;  Luo, Ping;  Tang, Ling;  Wang, Zhichao;  Gao, Peng;  Piao, Hailong;  Lu, Xin;  Xu, Guowang
Favorite  |  View/Download:30/0  |  Submit date:2017/12/19
a Small Amount Of Cells  Amino Acid Metabolism  High Throughput  Metabolic Profiling  
High-throughput metabolic profiling based on small amount of hepatic cells 期刊论文
ELECTROPHORESIS, 2017, 卷号: 38, 期号: 18, 页码: 2296-2303
Authors:  Zhou, Lina;  Yin, Peiyuan;  Luo, Ping;  Tang, Ling;  Wang, Zhichao;  Gao, Peng;  Piao, Hailong;  Lu, Xin;  Xu, Guowang
Favorite  |  View/Download:33/0  |  Submit date:2017/12/19
a Small Amount Of Cells  Amino Acid Metabolism  High Throughput  Metabolic Profiling  
Comparison of the inhibitory effects of tolcapone and entacapone against human UDP-glucuronosyltransferases 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2016, 卷号: 301, 页码: 42-49
Authors:  Lv, Xia;  Wang, Xin-Xin;  Hou, Jie;  Fang, Zhong-Ze;  Wu, Jing-Jing;  Cao, Yun-Feng;  Liu, Shu-Wen;  Ge, Guang-Bo;  Yang, Ling
Favorite  |  View/Download:3/0  |  Submit date:2019/06/20
Udp-glucosyltransferases  Entacapone  Tolcapone  Inhibitory Effects  Drug-drug Interactions (Ddi)