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Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu 期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 10
Authors:  Dai, Zi-Ru;  Ning, Jing;  Sun, Gui-Bo;  Wang, Ping;  Zhang, Feng;  Ma, Hong-Ping;  Zou, Li-Wei;  Hou, Jie;  Wu, Jing-Jing;  Ge, Guang-Bo;  Sun, Xiao-Bo;  Yang, Ling
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bufotalin  cytochrome P450 3A (CYP3A)  hydroxylation  human liver microsomes (HLMs)  docking simulations  
Short-chain chlorinated paraffins (SCCPs) induced thyroid disruption by enhancement of hepatic thyroid hormone influx and degradation in male Sprague Dawley rats 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2018, 卷号: 625, 页码: 657-666
Authors:  Gong, Yufeng;  Zhang, Haijun;  Geng, Ningbo;  Xing, Liguo;  Fan, Jingfeng;  Luo, Yun;  Song, Xiaoyao;  Ren, Xiaoqian;  Wang, Feidi;  Chen, Jiping
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Short-chain Chlorinated Paraffins  Thyroid Disruption  Hepatic Metabolism  Thyroid Hormone  Constitutive Androstane Receptor  
New Insights into SN-38 Glucuronidation: Evidence for the Important Role of UDP Glucuronosyltransferase 1A9 期刊论文
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2018, 卷号: 122, 期号: 4, 页码: 424-428
Authors:  Xiao, Ling;  Zhu, Liangliang;  Li, Wenjuan;  Li, Conghu;  Cao, Yunfeng;  Ge, Guangbo;  Sun, Xiaoyu
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Assessment of hepatic metabolism-dependent nephrotoxicity on an organs-on-a-chip microdevice 期刊论文
TOXICOLOGY IN VITRO, 2018, 卷号: 46, 页码: 1-8
Authors:  Li, Zhongyu;  Jiang, Lei;  Zhu, Yujuan;  Su, Wentao;  Xu, Cong;  Tao, Tingting;  Shi, Yang;  Qin, Jianhua
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Microfluidics  Drug Testing  Hepatic Metabolism  Nephrotoxicity  Organs-on-a-chip  
Paper supported long-term 3D liver co-culture model for the assessment of hepatotoxic drugs 期刊论文
TOXICOLOGY RESEARCH, 2018, 卷号: 7, 期号: 1, 页码: 13-21
Authors:  Wang, Yaqing;  Su, Wentao;  Wang, Li;  Jiang, Lei;  Liu, Yang;  Hui, Lijian;  Qin, Jianhua
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High-throughput metabolic profiling based on small amount of hepatic cells 期刊论文
ELECTROPHORESIS, 2017, 卷号: 38, 期号: 18, 页码: 2296-2303
Authors:  Zhou, Lina;  Yin, Peiyuan;  Luo, Ping;  Tang, Ling;  Wang, Zhichao;  Gao, Peng;  Piao, Hailong;  Lu, Xin;  Xu, Guowang
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a Small Amount Of Cells  Amino Acid Metabolism  High Throughput  Metabolic Profiling  
High-throughput metabolic profiling based on small amount of hepatic cells 期刊论文
ELECTROPHORESIS, 2017, 卷号: 38, 期号: 18, 页码: 2296-2303
Authors:  Zhou, Lina;  Yin, Peiyuan;  Luo, Ping;  Tang, Ling;  Wang, Zhichao;  Gao, Peng;  Piao, Hailong;  Lu, Xin;  Xu, Guowang
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a Small Amount Of Cells  Amino Acid Metabolism  High Throughput  Metabolic Profiling  
Comparison of the inhibitory effects of tolcapone and entacapone against human UDP-glucuronosyltransferases 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2016, 卷号: 301, 页码: 42-49
Authors:  Lv, Xia;  Wang, Xin-Xin;  Hou, Jie;  Fang, Zhong-Ze;  Wu, Jing-Jing;  Cao, Yun-Feng;  Liu, Shu-Wen;  Ge, Guang-Bo;  Yang, Ling
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Udp-glucosyltransferases  Entacapone  Tolcapone  Inhibitory Effects  Drug-drug Interactions (Ddi)  
A Laminated Microfluidic Device for Comprehensive Preclinical Testing in the Drug ADME Process 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6
Authors:  An, Fan;  Qu, Yueyang;  Luo, Yong;  Fang, Ning;  Liu, Yang;  Gao, Zhigang;  Zhao, Weijie;  Lin, Bingcheng
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New Insights into the Cytotoxic Mechanism of Hexabromocyclododecane from a Metabolomic Approach 期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2016, 卷号: 50, 期号: 6, 页码: 3145-3153
Authors:  Wang, Feidi;  Zhang, Haijun;  Geng, Ningbo;  Zhang, Baoqin;  Ren, Xiaoqian;  Chen, Jiping
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