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Inhibition of human CYP3A4 and CYP3A5 enzymes by gomisin C and gomisin G, two lignan analogs derived from Schisandra chinensis 期刊论文
FITOTERAPIA, 2017, 卷号: 119, 页码: 26-31
Authors:  Zhao, Jin;  Sun, Tao;  Wu, Jing-Jing;  Cao, Yun-Feng;  Fang, Zhong-Ze;  Sun, Hong-Zhi;  Zhu, Zhi-Tu;  Yang, Kun;  Liu, Yong-Zhe;  Gonzalez, Frank J.;  Yin, Jun
Favorite  |  View/Download:49/0  |  Submit date:2017/10/29
Gomisin c  Gomisin g  Cyp3a4  Cyp3a5  Inhibition  Herb-drug Interactions  
Diethylstilbestrol can effectively accelerate estradiol-17-O-glucuronidation; while potently inhibiting estradiol-3-O-glucuronidation 期刊论文
TOXICOLOGY IN VITRO, 2015, 卷号: 29, 期号: 1, 页码: 1569
Authors:  He W(何薇);  Wu JJ(吴敬敬);  Ning J(宁静);  Hou J(侯洁);  Xin H(辛红);  He YQ(何芋歧);  Ge GB(葛广波);  WeiXu
Adobe PDF(1254Kb)  |  Favorite  |  View/Download:81/38  |  Submit date:2015/11/16
Drug Metabolism and Pharmacokinetic Diversity of Ranunculaceae Medicinal 期刊论文
CURRENT DRUG METABOLISM, 2015, 卷号: 16, 期号: 1, 页码: 294
Authors:  Da-ChengHao;  Ge GB(葛广波);  Pei-GenXiao;  Wang P(王平);  Yang L(杨凌)
Adobe PDF(911Kb)  |  Favorite  |  View/Download:64/38  |  Submit date:2015/11/16
Herb-drug interaction prediction based on the high specific inhibition of andrographolide derivatives towards UDP-glucuronosyltransferase (UGT) 2B7 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2014, 卷号: 277, 期号: 1, 页码: 86-94
Authors:  Ma, Hai-Ying;  Sun, Dong-Xue;  Cao, Yun-Feng;  Ai, Chun-Zhi;  Qu, Yan-Qing;  Hu, Cui-Min;  Jiang, Changtao;  Dong, Pei-Pei;  Sun, Xiao-Yu;  Hong, Mo;  Tanaka, Naoki;  Gonzalez, Frank J.;  Ma, Xiao-Chi;  Fang, Zhong-Ze
Favorite  |  View/Download:55/0  |  Submit date:2015/11/17
Andrographolide Derivatives  Herb-drug Interaction (Hdi)  Udp-glucuronosyltransferases (Ugts)  Adverse Effects  
Structure-inhibition relationship of ginsenosides towards UDP-glucuronosyltransferases (UGTs) 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2013, 卷号: 267, 期号: 2, 页码: 149-154
Authors:  Fang, Zhong-Ze;  Cao, Yun-Feng;  Hu, Cui-Min;  Hong, Mo;  Sun, Xiao-Yu;  Ge, Guang-Bo;  Liu, Yong;  Zhang, Yan-Yan;  Yang, Ling;  Sun, Hong-Zhi
Favorite  |  View/Download:34/0  |  Submit date:2015/11/09
Ginsenosides  Udp-glucuronosyltransferases (Ugts)  Ginseng-drug Interaction  
Interactions between Phytochemicals from Traditional Chinese Medicines and Human Cytochrome P450 Enzymes 期刊论文
CURRENT DRUG METABOLISM, 2012, 卷号: 13, 期号: 5, 页码: 599-614
Authors:  Wu, Jing-Jing;  Ai, Chun-Zhi;  Liu, Yong;  Zhang, Yan-Yan;  Jiang, Miao;  Fan, Xu-Ran;  Lv, Ai-Ping;  Yang, Ling;  Yang L(杨凌)
Adobe PDF(227Kb)  |  Favorite  |  View/Download:321/69  |  Submit date:2013/10/11
Phytochemicals  Tcm  Cytochrome P450  Efficacy  Toxicity