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Recent progress and challenges in screening and characterization of UGT1A1 inhibitors 期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 2, 页码: 258-278
Authors:  Lv, Xia;  Xia, Yangliu;  Finel, Moshe;  Wu, Jingjing;  Ge, Guangbo;  Yang, Ling
Favorite  |  View/Download:2/0  |  Submit date:2019/06/20
UGT1A1 inhibitors  Drug/herbdrug interactions  Probe substrates  High-throughput screening  
Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu 期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 10
Authors:  Dai, Zi-Ru;  Ning, Jing;  Sun, Gui-Bo;  Wang, Ping;  Zhang, Feng;  Ma, Hong-Ping;  Zou, Li-Wei;  Hou, Jie;  Wu, Jing-Jing;  Ge, Guang-Bo;  Sun, Xiao-Bo;  Yang, Ling
Favorite  |  View/Download:3/0  |  Submit date:2019/06/20
bufotalin  cytochrome P450 3A (CYP3A)  hydroxylation  human liver microsomes (HLMs)  docking simulations  
New Insights into SN-38 Glucuronidation: Evidence for the Important Role of UDP Glucuronosyltransferase 1A9 期刊论文
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2018, 卷号: 122, 期号: 4, 页码: 424-428
Authors:  Xiao, Ling;  Zhu, Liangliang;  Li, Wenjuan;  Li, Conghu;  Cao, Yunfeng;  Ge, Guangbo;  Sun, Xiaoyu
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Amentoflavone is a potent broad-spectrum inhibitor of human UDP-glucuronosyltransferases 期刊论文
CHEMICO-BIOLOGICAL INTERACTIONS, 2018, 卷号: 284, 页码: 48-55
Authors:  Lv, Xia;  Zhang, Jian-Bin;  Wang, Xin-Xin;  Hu, Wen-Zhong;  Shi, Yu-Sheng;  Liu, Shu-Wen;  Hao, Da-Cheng;  Zhang, Wei-Dong;  Ge, Guang-Bo;  Hou, Jie;  Yang, Ling
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Amentoflavone  Udp-glucuronosyltransferases  Broad-spectrum Inhibitor  Herb-drug Interactions (Hdis)  
Acute exposure to crotonaldehyde induces dysfunction of immune system in male Wistar rats 期刊论文
JOURNAL OF TOXICOLOGICAL SCIENCES, 2018, 卷号: 43, 期号: 1-3, 页码: 33-44
Authors:  Wang, Limeng;  Yang, Zhihua;  Xu, Long;  Pan, Xiujie;  Liu, Xingyu;  Zhao, Junwei;  Li, Xiang;  Zhu, Maoxiang;  Xie, Jianping
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Crotonaldehyde  Male Wistar Rats  Immune System  
Study of a series of fluorophore-labeled artesunate derivatives Design, analysis and application 期刊论文
DYES AND PIGMENTS, 2017, 卷号: 146, 页码: 414-419
Authors:  Yang, Zihao;  Ge, Guangbo;  Liu, Fengyu;  Chen, Su-Shing;  Sun, Shiguo
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Artesunate (Art)  Fluorophore  Covalent Modification  
Study of a series of fluorophore-labeled artesunate derivatives Design, analysis and application 期刊论文
DYES AND PIGMENTS, 2017, 卷号: 146, 页码: 414-419
Authors:  Yang, Zihao;  Ge, Guangbo;  Liu, Fengyu;  Chen, Su-Shing;  Sun, Shiguo
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Artesunate (Art)  Fluorophore  Covalent Modification  
Comparison of the inhibition potentials of icotinib and erlotinib against human UDP-glucuronosyltransferase 1A1 期刊论文
ACTA PHARMACEUTICA SINICA B, 2017, 卷号: 7, 期号: 6, 页码: 657-664
Authors:  Cheng, Xuewei;  Lv, Xia;  Qu, Hengyan;  Li, Dandan;  Hu, Mengmeng;  Guo, Wenzhi;  Ge, Guangbo;  Dong, Ruihua
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Icotinib  Erlotinib  Ugt1a1  Inhibitory Effects  Drug-drug Interacts (Ddis)  
Comparative metabolism of DDAO benzoate in liver microsomes from various species 期刊论文
TOXICOLOGY IN VITRO, 2017, 卷号: 44, 页码: 280-286
Authors:  Ma, Hong-Ying;  Yang, Jia-Da;  Hou, Jie;  Zou, Li-Wei;  Jin, Qiang;  Hao, Da-Cheng;  Ning, Jing;  Ge, Guang-Bo;  Yang, Ling
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Ddab Hydrolysis  Carboxylesterase 2 (Ce2)  Species Differences  Liver Microsomes  
Comparative metabolism of DDAO benzoate in liver microsomes from various species 期刊论文
TOXICOLOGY IN VITRO, 2017, 卷号: 44, 页码: 280-286
Authors:  Ma, Hong-Ying;  Yang, Jia-Da;  Hou, Jie;  Zou, Li-Wei;  Jin, Qiang;  Hao, Da-Cheng;  Ning, Jing;  Ge, Guang-Bo;  Yang, Ling
Favorite  |  View/Download:47/0  |  Submit date:2017/12/19
Ddab Hydrolysis  Carboxylesterase 2 (Ce2)  Species Differences  Liver Microsomes