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Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu 期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 10
Authors:  Dai, Zi-Ru;  Ning, Jing;  Sun, Gui-Bo;  Wang, Ping;  Zhang, Feng;  Ma, Hong-Ping;  Zou, Li-Wei;  Hou, Jie;  Wu, Jing-Jing;  Ge, Guang-Bo;  Sun, Xiao-Bo;  Yang, Ling
Favorite  |  View/Download:6/0  |  Submit date:2019/06/20
bufotalin  cytochrome P450 3A (CYP3A)  hydroxylation  human liver microsomes (HLMs)  docking simulations  
Characterization of regio- and stereo-selective sulfation of bufadienolides: exploring the mechanism and providing insight into the structure-sulfation relationship by experimentation and molecular docking analysis 期刊论文
RSC ADVANCES, 2016, 卷号: 6, 期号: 7, 页码: 5774-5783
Authors:  Ning, Jing;  Cui, Yonglei;  Wang, Chao;  Dong, Peipei;  Ge, Guangbo;  Tian, Xiangge;  Hou, Jie;  Huo, Xiaokui;  Zhang, Baojing;  Ma, Tonghui;  Ma, Xiaochi
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Interspecies variation in phase I metabolism of bufalin in hepatic microsomes from mouse; rat; dog; minipig; monkey; and human 期刊论文
XENOBIOTICA, 2015, 卷号: 45, 期号: 11, 页码: 954
Authors:  Ning J(宁静);  JieHou;  Wang P(王平);  Wu JJ(吴敬敬);  Dai ZR(戴子茹);  Zou LW(邹立伟);  WeiLi;  Ge GB(葛广波);  Xiao-ChiMa;  Yang L(杨凌)
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Purification of bufadienolides from the skin of Bufo bufo gargarizans Cantor with positively charged C18 column 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014, 卷号: 92, 页码: 105-113
Authors:  Li, Xiaolong;  Guo, Zhimou;  Wang, Chaoran;  Shen, Aijin;  Liu, Yanfang;  Zhang, Xiuli;  Zhao, Weijie;  Liang, Xinmiao;  Liu YF(刘艳芳);  Liang XM(梁鑫淼)
Adobe PDF(745Kb)  |  Favorite  |  View/Download:554/129  |  Submit date:2014/09/11
Purification  Bufadienolides  Bufo Bufo Gargarizans Cantor  Reversed-phase Liquid Chromatography  Positively Charged C18