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Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu 期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 10
Authors:  Dai, Zi-Ru;  Ning, Jing;  Sun, Gui-Bo;  Wang, Ping;  Zhang, Feng;  Ma, Hong-Ping;  Zou, Li-Wei;  Hou, Jie;  Wu, Jing-Jing;  Ge, Guang-Bo;  Sun, Xiao-Bo;  Yang, Ling
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bufotalin  cytochrome P450 3A (CYP3A)  hydroxylation  human liver microsomes (HLMs)  docking simulations  
Diethylstilbestrol can effectively accelerate estradiol-17-O-glucuronidation; while potently inhibiting estradiol-3-O-glucuronidation 期刊论文
TOXICOLOGY IN VITRO, 2015, 卷号: 29, 期号: 1, 页码: 1569
Authors:  He W(何薇);  Wu JJ(吴敬敬);  Ning J(宁静);  Hou J(侯洁);  Xin H(辛红);  He YQ(何芋歧);  Ge GB(葛广波);  WeiXu
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Drug Metabolism and Pharmacokinetic Diversity of Ranunculaceae Medicinal 期刊论文
CURRENT DRUG METABOLISM, 2015, 卷号: 16, 期号: 1, 页码: 294
Authors:  Da-ChengHao;  Ge GB(葛广波);  Pei-GenXiao;  Wang P(王平);  Yang L(杨凌)
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Interspecies variation in phase I metabolism of bufalin in hepatic microsomes from mouse; rat; dog; minipig; monkey; and human 期刊论文
XENOBIOTICA, 2015, 卷号: 45, 期号: 11, 页码: 954
Authors:  Ning J(宁静);  JieHou;  Wang P(王平);  Wu JJ(吴敬敬);  Dai ZR(戴子茹);  Zou LW(邹立伟);  WeiLi;  Ge GB(葛广波);  Xiao-ChiMa;  Yang L(杨凌)
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Quantitative analysis of cytochrome P450 isoforms in human liver microsomes by the combination of proteomics and chemical probe-based assay 期刊论文
PROTEOMICS, 2014, 卷号: 14, 期号: 16, 页码: 1943-1951
Authors:  Liu, Xidong;  Hu, Lianghai;  Ge, Guangbo;  Yang, Bo;  Ning, Jing;  Sun, Shixin;  Yang, Ling;  Pors, Klaus;  Gu, Jingkai;  XidongLiu;  Ge GB(葛广波);  JingkaiGu
Adobe PDF(670Kb)  |  Favorite  |  View/Download:92/45  |  Submit date:2015/11/16
Biomedicine  Cytochrome P450  Mrm  Protein Quantification  Stable Isotope Labeling  
Deoxyschizandrin, a Naturally Occurring Lignan, Is a Specific Probe Substrate of Human Cytochrome P450 3A 期刊论文
DRUG METABOLISM AND DISPOSITION, 2014, 卷号: 42, 期号: 1, 页码: 94-104
Authors:  Wu, Jingjing;  Cao, Yunfeng;  Zhang, Yanyan;  Liu, Yong;  Hong, James Y.;  Zhu, Liangliang;  Ge, Guangbo;  Yang, Ling;  Yang L(杨凌)
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Interactions between Phytochemicals from Traditional Chinese Medicines and Human Cytochrome P450 Enzymes 期刊论文
CURRENT DRUG METABOLISM, 2012, 卷号: 13, 期号: 5, 页码: 599-614
Authors:  Wu, Jing-Jing;  Ai, Chun-Zhi;  Liu, Yong;  Zhang, Yan-Yan;  Jiang, Miao;  Fan, Xu-Ran;  Lv, Ai-Ping;  Yang, Ling;  Yang L(杨凌)
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Phytochemicals  Tcm  Cytochrome P450  Efficacy  Toxicity  
Bioactivation of herbal constituents: simple alerts in the complex system 期刊论文
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, 2011, 卷号: 7, 期号: 8, 页码: 989-1007
Authors:  Fang, Zhong-Ze;  Zhang, Yan-Yan;  Wang, Xiu-Li;  Cao, Yun-Feng;  Huo, Hong;  Yang, Ling;  Yang L(杨凌)
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Bioactivation  Herbal Medicines  Herbal Toxicity  Herb-drug Interactions  
Comparative Metabolism of Cinobufagin in Liver Microsomes from Mouse, Rat, Dog, Minipig, Monkey, and Human 期刊论文
DRUG METABOLISM AND DISPOSITION, 2011, 卷号: 39, 期号: 4, 页码: 675-682
Authors:  Ma, Xiao-Chi;  Ning, Jing;  Ge, Guang-Bo;  Liang, Si-Cheng;  Wang, Xiu-Li;  Zhang, Bao-Jing;  Huang, Shan-Shan;  Li, Jing-Kui;  Yang, Ling;  Yang L(杨凌)
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Substrate-dependent modulation of CYP3A catalytic activity by erlotinib 期刊论文
Acta Pharmacologica Sinica(中国期刊), 2011, 卷号: 3, 期号: 待补充, 页码: 399
Authors:  Dong PP(董佩佩);  Fang ZZ(房中则);  Zhang YY(张延延);  Ge GB(葛广波);  Mao YX(毛玉玺);  Zhu LL(朱亮亮);  YanqingQU;  Li W(李巍);  LimingWANG;  ChangxiaoLIU;  Yang L(杨凌)
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