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Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu 期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 10
Authors:  Dai, Zi-Ru;  Ning, Jing;  Sun, Gui-Bo;  Wang, Ping;  Zhang, Feng;  Ma, Hong-Ping;  Zou, Li-Wei;  Hou, Jie;  Wu, Jing-Jing;  Ge, Guang-Bo;  Sun, Xiao-Bo;  Yang, Ling
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bufotalin  cytochrome P450 3A (CYP3A)  hydroxylation  human liver microsomes (HLMs)  docking simulations  
Methyl-Hispolon from Phellinus lonicerinus (Agaricomycetes) Affects Estrogen Signals in MCF-7 Breast Cancer Cells and Premature Aging in Rats 期刊论文
INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS, 2019, 卷号: 21, 期号: 4, 页码: 381-392
Authors:  Wang, Junzhi;  Lv, Huifang;  Chen, Beiyan;  Huang, Wenfeng;  Wang, Ailing;  Liu, Lanqing;  He, Haibo;  Chen, Jianfeng;  Li, Shi;  Deng, Wei-Qiao
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methyl-hispolon  estrogen signals  phytoestrogen  hormone replacement therapy  Phellinus lonicerinus  medicinal mushrooms  
Characterization and structure-activity relationship studies of flavonoids as inhibitors against human carboxylesterase 2 期刊论文
BIOORGANIC CHEMISTRY, 2018, 卷号: 77, 页码: 320-329
Authors:  Weng, Zi-Miao;  Ge, Guang-Bo;  Dou, Tong-Yi;  Wang, Ping;  Liu, Ping-Kun;  Tian, Xin-Hui;  Qiao, Nan;  Yu, Yang;  Zou, Li-Wei;  Zhou, Qi;  Zhang, Wei-Dong;  Hou, Jie
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Flavonoids  Human Carboxylesterase 2 (Hce2)  Structure-inhibition Relationships  Selectivity  Inhibition Mechanism  
Molecular interaction study of flavonoids with human serum albumin using native mass spectrometry and molecular modeling 期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2018, 卷号: 410, 期号: 3, 页码: 827-837
Authors:  Wang, Bohong;  Qin, Qian;  Chang, Mengmeng;  Li, Shuyan;  Shi, Xianzhe;  Xu, Guowang
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Native Mass Spectrometry  Noncovalent Interaction  Human Serum Albumin  Flavonoids  
A Practical and High-Affinity Fluorescent Probe for Uridine Diphosphate Glucuronosyltransferase 1A1: A Good Surrogate for Bilirubin 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 23, 页码: 9664-9675
Authors:  Lv, Xia;  Feng, Lei;  Ai, Chun-Zhi;  Hou, Jie;  Wang, Ping;  Zou, Li-Wei;  Cheng, Jie;  Ge, Guang-Bo;  Cui, Jing-Nan;  Yang, Ling
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Structure-activity relationships of flavonoids as natural inhibitors against E. coli beta-glucuronidase 期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2017, 卷号: 109, 页码: 975-983
Authors:  Weng, Zi-Miao;  Wang, Ping;  Ge, Guang-Bo;  Dai, Zi-Ru;  Wu, Da-Chang;  Zou, Li-Wei;  Dou, Tong-Yi;  Zhang, Tong-Yan;  Yang, Ling;  Hou, Jie
Favorite  |  View/Download:10/0  |  Submit date:2019/06/20
Flavonoids  E. Coli bE.a-glucuronidasE.  Structure-inhibition Relationships  Scutellarein  Luteolin  
Structure-Activity Relationships of Pentacyclic Triterpenoids as Potent and Selective Inhibitors against Human Carboxylesterase 1 期刊论文
FRONTIERS IN PHARMACOLOGY, 2017, 卷号: 8
Authors:  Zou, Li-Wei;  Dou, Tong-Yi;  Wang, Ping;  Lei, Wei;  Weng, Zi-Miao;  Hou, Jie;  Wang, Dan-Dan;  Fan, Yi-Ming;  Zhang, Wei-Dong;  Ge, Guang-Bo;  Yang, Ling
Favorite  |  View/Download:45/0  |  Submit date:2017/10/29
Human Carboxylesterase 1 (Hce1)  Ursolic Acid  Oleanolic Acid  Structure-activity Relationship (Sar)  Selective Inhibitors  
Inhibition of human CYP3A4 and CYP3A5 enzymes by gomisin C and gomisin G, two lignan analogs derived from Schisandra chinensis 期刊论文
FITOTERAPIA, 2017, 卷号: 119, 页码: 26-31
Authors:  Zhao, Jin;  Sun, Tao;  Wu, Jing-Jing;  Cao, Yun-Feng;  Fang, Zhong-Ze;  Sun, Hong-Zhi;  Zhu, Zhi-Tu;  Yang, Kun;  Liu, Yong-Zhe;  Gonzalez, Frank J.;  Yin, Jun
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Gomisin c  Gomisin g  Cyp3a4  Cyp3a5  Inhibition  Herb-drug Interactions  
Interaction of Metal Ions with the His13-His14 Sequence Relevant to Alzheimer’s Disease 期刊论文
JOURNAL OF PHYSICAL CHEMISTRY A, 2015, 卷号: 119, 期号: 1, 页码: 3528
Authors:  孔祥涛;  赵志;  雷鑫;  张冰冰;  戴东旭;  江凌
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In silico research to assist the investigation of carboxamide derivatives as potent TRPV1 antagonists 期刊论文
MOLECULAR BIOSYSTEMS, 2015, 卷号: 11, 期号: 11, 页码: 2885-2899
Authors:  Wang, Jinghui;  Li, Yan;  Yang, Yinfeng;  Du, Jian;  Zhang, Shuwei;  Yang, Ling
Favorite  |  View/Download:138/0  |  Submit date:2015/11/17