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Discovery of novel antagonists on (2)-adrenoceptor from natural products using a label-free cell phenotypic assay 期刊论文
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2018, 卷号: 391, 期号: 12, 页码: 1411-1420
Authors:  Zhang, Pengyu;  Wang, Jixia;  Zhao, Ying;  Zhang, Xiuli;  Qu, Lala;  Wang, Chaoran;  Feng, Jiatao;  Wang, Anhui;  Zhou, Weijia;  Liu, Yanfang;  Hou, Tao;  Zhou, Han;  Wang, Zhiwei;  Liang, Xinmiao
Favorite  |  View/Download:2/0  |  Submit date:2019/06/20
beta(2)-Adrenoceptor  Antagonist  Natural product  Label-free cell phenotypic assay  
Saikosaponin D from Radix Bupleuri suppresses triple-negative breast cancer cell growth by targeting beta-catenin signaling 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2018, 卷号: 108, 页码: 724-733
Authors:  Wang, Jixia;  Qi, Huan;  Zhang, Xiuli;  Si, Wei;  Xu, Fangfang;  Hou, Tao;  Zhou, Han;  Wang, Anhui;  Li, Guohui;  Liu, Yanfang;  Fang, Ye;  Piao, Hai-long;  Liang, Xinmiao
Favorite  |  View/Download:3/0  |  Submit date:2019/06/20
Triple-negative breast cancer  Saikosaponin D  Radix Bupleuri  Wnt/beta-catenin  
Discovery of beta(2)-adrenoceptor agonists in Curcuma zedoaria Rosc using label-free cell phenotypic assay combined with two-dimensional liquid chromatography 期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2018, 卷号: 1577, 页码: 59-65
Authors:  Zhou, Weijia;  Wang, Jixia;  Zhao, Yaopeng;  Yu, Long;  Fang, Ye;  Jin, Hongli;  Zhou, Han;  Zhang, Pengyu;  Liu, Yanfang;  Zhang, Xiuli;  Liang, Xinmiao
Favorite  |  View/Download:3/0  |  Submit date:2019/06/20
Curcuma zedoaria Rosc  beta(2)-adrenoceptor agonists  Diarylheptanoids  Label-free cell phenotypic assay  Two-dimensional liquid chromatography  
Discovery of new muscarinic acetylcholine receptor antagonists from Scopolia tangutica 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7
Authors:  Du, Nana;  Liu, Yanfang;  Zhang, Xiuli;  Wang, Jixia;  Zhao, Jianqiang;  He, Jian;  Zhou, Han;  Mei, Lijuan;  Liang, Xinmiao
Favorite  |  View/Download:2/0  |  Submit date:2019/06/20
Discovery of 2H-Chromen-2-one Derivatives as G Protein-Coupled Receptor-35 Agonists 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 1, 页码: 362-372
Authors:  Wei, Lai;  Wang, Jixia;  Zhang, Xiuli;  Wang, Ping;  Zhao, Yaopeng;  Li, Jiaqi;  Hou, Tao;  Qu, Lala;  Shi, Liying;  Liang, Xinmiao;  Fang, Ye
Favorite  |  View/Download:37/0  |  Submit date:2017/10/29
Recent development in liquid chromatography stationary phases for separation of Traditional Chinese Medicine components 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2016, 卷号: 130, 页码: 336-346
Authors:  Jin, Hongli;  Liu, Yanfang;  Guo, Zhimou;  Wang, Jixia;  Zhang, Xiuli;  Wang, Chaoran;  Liang, Xinmiao
Favorite  |  View/Download:2/0  |  Submit date:2019/06/20
Traditional Chinese Medicines  Stationary Phases  High Performance Liquid Chromatography  Hydrophilic Interaction Liquid Chromatography  Ultra High-performance Liquid Chromatography  
Separation and characterization of bufadienolides in toad skin using two-dimensional normal-phase liquid chromatography x reversed-phase liquid chromatography coupled with mass spectrometry 期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2016, 卷号: 1026, 页码: 67-74
Authors:  Zhang, Yun;  Jin, Hongli;  Li, Xiaolong;  Zhao, Jianqiang;  Guo, Xiujie;  Wang, Jixia;  Guo, Zhimou;  Zhang, Xiuli;  Tao, Yanduo;  Liu, Yanfang;  Chen, Deliang;  Liang, Xinmiao
Favorite  |  View/Download:1/0  |  Submit date:2019/06/20
Bufadienolides  Normal-phase Liquid Chromatography  Two-dimensional Liquid Chromatography  Ms/ms  Toad Skin  
Label-free cell phenotypic profiling and pathway deconvolution of neurotensin receptor-1 期刊论文
PHARMACOLOGICAL RESEARCH, 2016, 卷号: 108, 页码: 39-45
Authors:  Hou, Tao;  Shi, Liying;  Wang, Jixia;  Wei, Lai;  Qu, Lala;  Zhang, Xiuli;  Liang, Xinmiao
Favorite  |  View/Download:1/0  |  Submit date:2019/06/20
Neurotensin Receptor-1  Pathway  Label-free Cell Phenotypic Profiling  Biased Agonism  
Anti-gastric cancer activity in three-dimensional tumor spheroids of bufadienolides 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6
Authors:  Wang, Jixia;  Zhang, Xiuli;  Li, Xiaolong;  Zhang, Yun;  Hou, Tao;  Wei, Lai;  Qu, Lala;  Shi, Liying;  Liu, Yanfang;  Zou, Lijuan;  Liang, Xinmiao
Favorite  |  View/Download:2/0  |  Submit date:2019/06/20
Discovery of new targets of phenolic acids in Danshen using label-free cell phenotypic assay 期刊论文
RSC Advances, 2016, 卷号: 5, 期号: 0, 页码: 25768
Authors:  Wang JX(王纪霞);  Hou T(侯滔);  Wei L(魏来);  Shi LY(史丽颖);  He J(何牮);  Nan Zhou;  Sun GW(孙广炜);  Zhang XL(张秀莉);  Liang XM(梁鑫淼)
Favorite  |  View/Download:32/0  |  Submit date:2016/11/24