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Inhibition of human CYP3A4 and CYP3A5 enzymes by gomisin C and gomisin G, two lignan analogs derived from Schisandra chinensis 期刊论文
FITOTERAPIA, 2017, 卷号: 119, 页码: 26-31
Authors:  Zhao, Jin;  Sun, Tao;  Wu, Jing-Jing;  Cao, Yun-Feng;  Fang, Zhong-Ze;  Sun, Hong-Zhi;  Zhu, Zhi-Tu;  Yang, Kun;  Liu, Yong-Zhe;  Gonzalez, Frank J.;  Yin, Jun
Favorite  |  View/Download:46/0  |  Submit date:2017/10/29
Gomisin c  Gomisin g  Cyp3a4  Cyp3a5  Inhibition  Herb-drug Interactions  
New insights into the risk of phthalates: Inhibition of UDP-glucuronosyltransferases (vol 144, pg 1966, 2015) 期刊论文
CHEMOSPHERE, 2016, 卷号: 151, 页码: 357-357
Authors:  Liu, Xin;  Cao, Yun-Feng;  Ran, Rui-Xue;  Dong, Pei-Pei;  Gonzalez, Frank J.;  XueWu;  Huang, Ting;  Chen, Jian-Xin;  Fu, Zhi-Wei;  Li, Rong-Shan;  Liu, Yong-Zhe;  Sun, Hong-Zhi;  Fang, Zhong-Ze
Favorite  |  View/Download:3/0  |  Submit date:2019/06/20
New insights into the risk of phthalates: Inhibition of UDP-glucuronosyltransferases 期刊论文
CHEMOSPHERE, 2016, 卷号: 144, 页码: 1966-1972
Authors:  Liu, Xin;  Cao, Yun-Feng;  Ran, Rui-Xue;  Dong, Pei-Pei;  Gonzalez, Frank J.;  Wu, Xue;  Huang, Ting;  Chen, Jian-Xin;  Fu, Zhi-Wei;  Li, Rong-Shan;  Liu, Yong-Zhe;  Sun, Hong-Zhi;  Fang, Zhong-Ze
Favorite  |  View/Download:7/0  |  Submit date:2019/06/20
Phthalates  Udp-glucuronosyltransferases (Ugts)  Di-n-octyl Ortho-phthalate (Dnop)  Diphenyl Phthalate (Dphp)  
Irinotecan (CPT-11)-induced elevation of bile acids potentiates suppression of IL-10 expression 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2016, 卷号: 291, 页码: 21-27
Authors:  Fang, Zhong-Ze;  Zhang, Dunfang;  Cao, Yun-Feng;  Xie, Cen;  Lu, Dan;  Sun, Dong-Xue;  Tanaka, Naoki;  Jiang, Changtao;  Chen, Qianming;  Chen, Yu;  Wang, Haina;  Gonzalez, Frank J.
Favorite  |  View/Download:7/0  |  Submit date:2019/06/20
Irinotecan (Cpt-11)  Metabolomics  Bile Acids  Interleukin-10  
Tissue and species differences in the glucuronidation of glabridin with UDP-glucuronosyltransferases 期刊论文
CHEMICO-BIOLOGICAL INTERACTIONS, 2015, 卷号: 231, 页码: 90-97
Authors:  Guo, Bin;  Fang, Zhongze;  Yang, Lu;  Xiao, Ling;  Xia, Yangliu;  Gonzalez, Frank J.;  Zhu, Liangliang;  Cao, Yunfeng;  Ge, Guangbo;  Yang, Ling;  Sun, Hongzhi
Favorite  |  View/Download:60/0  |  Submit date:2015/11/17
Glabridin  Glucuronidation  Udp-glucuronosyltransferases  Species Differences  
Regulation profile of phosphatidylcholines (PCs) and lysophosphatidylcholines (LPCs) components towards UDP-glucuronosyltransferases (UGTs) isoforms 期刊论文
XENOBIOTICA, 2015, 卷号: 45, 期号: 3, 页码: 197-206
Authors:  Gao, Xin;  Qu, Hengyan;  Ai, Chun-Zhi;  Cao, Yun-Feng;  Huang, Ting;  Chen, Jian-Xing;  Zeng, Jia;  Sun, Xiao-Yu;  Hong, Mo;  Gonzalez, Frank J.;  Liu, Zeyuan;  Fang, Zhong-Ze
Favorite  |  View/Download:94/0  |  Submit date:2015/11/17
Allosteric Activation  Lysophosphatidylcholines  Phosphatidylcholine  Udp-glucuronosyltransferases  
Metabolic profiling of praziquantel enantiomers 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2014, 卷号: 90, 期号: 2, 页码: 166-178
Authors:  Wang, Haina;  Fang, Zhong-Ze;  Zheng, Yang;  Zhou, Kun;  Hu, Changyan;  Krausz, Kristopher W.;  Sun, Dequn;  Idle, Jeffrey R.;  Gonzalez, Frank J.
Favorite  |  View/Download:46/0  |  Submit date:2015/11/17
Cytochromes P450  Enantioselective Metabolism  In Silica Metabolomics  Praziquantel  
Herb-drug interaction prediction based on the high specific inhibition of andrographolide derivatives towards UDP-glucuronosyltransferase (UGT) 2B7 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2014, 卷号: 277, 期号: 1, 页码: 86-94
Authors:  Ma, Hai-Ying;  Sun, Dong-Xue;  Cao, Yun-Feng;  Ai, Chun-Zhi;  Qu, Yan-Qing;  Hu, Cui-Min;  Jiang, Changtao;  Dong, Pei-Pei;  Sun, Xiao-Yu;  Hong, Mo;  Tanaka, Naoki;  Gonzalez, Frank J.;  Ma, Xiao-Chi;  Fang, Zhong-Ze
Favorite  |  View/Download:55/0  |  Submit date:2015/11/17
Andrographolide Derivatives  Herb-drug Interaction (Hdi)  Udp-glucuronosyltransferases (Ugts)  Adverse Effects  
A model of in vitro UDP-glucuronosyltransferase inhibition by bile acids predicts possible metabolic disorders 期刊论文
JOURNAL OF LIPID RESEARCH, 2013, 卷号: 54, 期号: 12, 页码: 3334-3344
Authors:  Fang, Zhong-Ze;  He, Rong-Rong;  Cao, Yun-Feng;  Tanaka, Naoki;  Jiang, Changtao;  Krausz, Kristopher W.;  Qi, Yunpeng;  Dong, Pei-Pei;  Ai, Chun-Zhi;  Sun, Xiao-Yu;  Hong, Mo;  Ge, Guang-Bo;  Gonzalez, Frank J.;  Ma, Xiao-Chi;  Sun, Hong-Zhi
Favorite  |  View/Download:75/0  |  Submit date:2015/11/09
Cholestasis  Endobiotics  Structure-udp-glucuronosyltransferase Inhibition Relationship  Xenobiotics