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Inhibitory effects of tanshinones towards the catalytic activity of UDP-glucuronosyltransferases (UGTs) 期刊论文
PHARMACEUTICAL BIOLOGY, 2017, 卷号: 55, 期号: 1, 页码: 1703-1709
Authors:  Zhang, Xu-Xin;  Cao, Yun-Feng;  Wang, Li-Xuan;  Yuan, Xiao-Lin;  Fang, Zhong-Ze
Favorite  |  View/Download:30/0  |  Submit date:2017/10/29
Enzyme Inhibition  Herb-drug Interaction  In Vitro screenIng  In vitro-In Vivo Extrapolation (Iv-ive)  
Inhibition behavior of fructus psoraleae's ingredients towards human carboxylesterase 1 (hCES1) 期刊论文
XENOBIOTICA, 2016, 卷号: 46, 期号: 6, 页码: 503-510
Authors:  Sun, Dong-Xue;  Ge, Guang-Bo;  Dong, Pei-Pei;  Cao, Yun-Feng;  Fu, Zhi-Wei;  Ran, Rui-Xue;  Wu, Xue;  Zhang, Yan-Yan;  Hua, Hui-Ming;  Zhao, Zhenying;  Fang, Zhong-Ze
Favorite  |  View/Download:4/0  |  Submit date:2019/06/20
Herb-drug Interaction  Toxicity  Human Carboxylesterase 1 (Ces1)  Fructus Psoraleae  
Herb-drug interaction prediction based on the high specific inhibition of andrographolide derivatives towards UDP-glucuronosyltransferase (UGT) 2B7 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2014, 卷号: 277, 期号: 1, 页码: 86-94
Authors:  Ma, Hai-Ying;  Sun, Dong-Xue;  Cao, Yun-Feng;  Ai, Chun-Zhi;  Qu, Yan-Qing;  Hu, Cui-Min;  Jiang, Changtao;  Dong, Pei-Pei;  Sun, Xiao-Yu;  Hong, Mo;  Tanaka, Naoki;  Gonzalez, Frank J.;  Ma, Xiao-Chi;  Fang, Zhong-Ze
Favorite  |  View/Download:49/0  |  Submit date:2015/11/17
Andrographolide Derivatives  Herb-drug Interaction (Hdi)  Udp-glucuronosyltransferases (Ugts)  Adverse Effects  
Glycyrrhetinic Acid Exhibits Strong Inhibitory Effects Towards UDP-Glucuronosyltransferase (UGT) 1A3 and 2B7 期刊论文
PHYTOTHERAPY RESEARCH, 2013, 卷号: 27, 期号: 9, 页码: 1358-1361
Authors:  Huang, Yin-Peng;  Cao, Yun-Feng;  Fang, Zhong-Ze;  Zhang, Yan-Yan;  Hu, Cui-Min;  Sun, Xiao-Yu;  Yu, Zhen-Wen;  Zhu, Xu;  Hong, Mo;  Yang, Lu;  Sun, Hong-Zhi
Favorite  |  View/Download:44/0  |  Submit date:2015/11/09
Licorice  Glycyrrhizic Acid  Glycyrrhetinic Acid  Udp-glucuronosyltransferases (Ugts)  Herb-drug Interaction  
The Inhibitory Effect of 20(S)-Protopanaxatriol (ppt) Towards UGT1A1 and UGT2B7 期刊论文
PHYTOTHERAPY RESEARCH, 2013, 卷号: 27, 期号: 4, 页码: 628-632
Authors:  He, Ya-Jun;  Fang, Zhong-Ze;  Ge, Guang-Bo;  Jiang, Peng;  Jin, Hui-Zi;  Zhang, Wei-Dong;  Yang, Ling
Favorite  |  View/Download:27/0  |  Submit date:2015/11/09
Ginseng  Udp-glucuronosyltransferases (Ugts)  Herb-drug Interaction  
Cryptotanshinone and dihydrotanshinone I exhibit strong inhibition towards human liver microsome (HLM)-catalyzed propofol glucuronidation 期刊论文
FITOTERAPIA, 2013, 卷号: 85, 页码: 109-113
Authors:  Cong, Ming;  Hu, Cui-Min;  Cao, Yun-Feng;  Fang, Zhong-Ze;  Tang, Shu-Hong;  Wang, Jia-Rui;  Luo, Jun-Sheng
Favorite  |  View/Download:21/0  |  Submit date:2015/11/09
Danshen  Udp-glucuronosyltransferases (Ugts)  Herb-drug Interaction  
Strong inhibition of deoxyschizandrin and schisantherin A toward UDP-glucuronosyltransferase (UGT) 1A3 indicating UGT inhibition-based herb-drug interaction 期刊论文
FITOTERAPIA, 2012, 卷号: 83, 期号: 8, 页码: 1415-1419
Authors:  Liu, Cong;  Cao, Yun-Feng;  Fang, Zhong-Ze;  Zhang, Yan-Yan;  Hu, Cui-Min;  Sun, Xiao-Yu;  Huang, Ting;  Zeng, Jia;  Fan, Xu-Ran;  Hong, Mo
Favorite  |  View/Download:30/0  |  Submit date:2015/11/13
Deoxyschizandrin  Udp-glucuronosyltransferases (Ugts)  Herb-drug Interaction  
Identification of Cytochrome P450 (CYP) Isoforms involved in the Metabolism of Corynoline, and Assessment of its Herb-Drug Interactions 期刊论文
PHYTOTHERAPY RESEARCH, 2011, 卷号: 25, 期号: 2, 页码: 256-263
Authors:  Fang, Zhong-Ze;  Zhang, Yan-Yan;  Ge, Guang-Bo;  Liang, Si-Cheng;  Sun, Dong-Xue;  Zhu, Liang-Liang;  Dong, Pei-Pei;  Cao, Yun-Feng;  Yang, Ling
Favorite  |  View/Download:32/0  |  Submit date:2015/11/12
Corynoline  Cytochrome P450 (Cyp)  Drug-herb Interaction  Time-dependent Inhibition (Tdi)