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Saxagliptin alters bile acid profiles and yields metabolic benefits in drug-naive overweight or obese type 2 diabetes patient 期刊论文
JOURNAL OF DIABETES, 2019, 页码: 11
Authors:  Li, Wen;  Liu, Ruixin;  Li, Xuelin;  Tao, Bei;  Zhai, Nan;  Wang, Xiaolin;  Li, Qi;  Zhang, Yifei;  Gu, Weiqiong;  Wang, Weiqing;  Ning, Guang
Favorite  |  View/Download:2/0  |  Submit date:2019/12/02
bile acids  dipeptidyl peptidase-4 inhibitor  obesity  saxagliptin  type 2 diabetes  
Operando dual beam FTIR spectroscopy unravels the promotional effect of Zn on HZSM-5 in iso-butane aromatization 期刊论文
CATALYSIS SCIENCE & TECHNOLOGY, 2019, 卷号: 9, 期号: 7, 页码: 1609-1620
Authors:  Liu, Jiaxu;  He, Ning;  Zhou, Wei;  Shu, Miao;  Lin, Long;  Wang, Jilei;  Si, Rui;  Xiong, Guang;  Xin, Qin;  Guo, Hongchen
Favorite  |  View/Download:6/0  |  Submit date:2019/06/20
Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu 期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 10
Authors:  Dai, Zi-Ru;  Ning, Jing;  Sun, Gui-Bo;  Wang, Ping;  Zhang, Feng;  Ma, Hong-Ping;  Zou, Li-Wei;  Hou, Jie;  Wu, Jing-Jing;  Ge, Guang-Bo;  Sun, Xiao-Bo;  Yang, Ling
Favorite  |  View/Download:8/0  |  Submit date:2019/06/20
bufotalin  cytochrome P450 3A (CYP3A)  hydroxylation  human liver microsomes (HLMs)  docking simulations  
Plasma bile acid changes in type 2 diabetes correlated with insulin secretion in two-step hyperglycemic clamp 期刊论文
JOURNAL OF DIABETES, 2018, 卷号: 10, 期号: 11, 页码: 874-885
Authors:  Wang, Shujie;  Deng, Yuying;  Xie, Xiaoyan;  Ma, Jing;  Xu, Min;  Zhao, Xinjie;  Gu, Weiqiong;  Hong, Jie;  Wang, Weiqing;  Xu, Guowang;  Ning, Guang;  Gu, Yanyun;  Zhang, Yifei
Favorite  |  View/Download:4/0  |  Submit date:2019/06/20
bile acid  hyperglycemic clamp  insulin secretion  type 2 diabetes mellitus  
Identification and characterization of human UDP-glucuronosyltransferases responsible for xanthotoxol glucuronidation 期刊论文
XENOBIOTICA, 2018, 卷号: 48, 期号: 2, 页码: 109-116
Authors:  He, Guiyuan;  Troberg, Johanna;  Lv, Xia;  Xia, Yang-Liu;  Zhu, Liang-Liang;  Ning, Jing;  Ge, Guang-Bo;  Finel, Moshe;  Yang, Ling
Favorite  |  View/Download:3/0  |  Submit date:2019/06/20
Intestinal Glucuronidation  Udp-glucuronosyltransferases  Xanthotoxol  
USP10 suppresses tumor progression by inhibiting mTOR activation in hepatocellular carcinoma 期刊论文
CANCER LETTERS, 2018, 卷号: 436, 页码: 139-148
Authors:  Lu, Chang;  Ning, Zhen;  Wang, Aman;  Ghen, Di;  Liu, Xiaolong;  Xia, Tian;  Tekcham, Dinesh Singh;  Wang, Wen;  Li, Tongming;  Liu, Xiumei;  Liu, Jing;  Qi, Huan;  Luo, Haifeng;  Du, Jian;  Ma, Chi;  Yan, Qiu;  Liu, Jiwei;  Xu, Guowang;  Piao, Hai-long;  Tan, Guang
Favorite  |  View/Download:8/0  |  Submit date:2019/06/20
HCC  USP10  Deubiquitination  mTOR  
Analyses of gut microbiota and plasma bile acids enable stratification of patients for antidiabetic treatment 期刊论文
NATURE COMMUNICATIONS, 2017, 卷号: 8
Authors:  Gu, Yanyun;  Wang, Xiaokai;  Li, Junhua;  Zhang, Yifei;  Zhong, Huanzi;  Liu, Ruixin;  Zhang, Dongya;  Feng, Qiang;  Xie, Xiaoyan;  Hong, Jie;  Ren, Huahui;  Liu, Wei;  Ma, Jing;  Su, Qing;  Zhang, Hongmei;  Yang, Jialin;  Wang, Xiaoling;  Zhao, Xinjie;  Gu, Weiqiong;  Bi, Yufang;  Peng, Yongde;  Xu, Xiaoqiang;  Xia, Huihua;  Li, Fang;  Xu, Xun;  Yang, Huanming;  Xu, Guowang;  Madsen, Lise;  Kristiansen, Karsten;  Ning, Guang;  Wang, Weiqing
Favorite  |  View/Download:11/0  |  Submit date:2019/06/20
Comparative metabolism of DDAO benzoate in liver microsomes from various species 期刊论文
TOXICOLOGY IN VITRO, 2017, 卷号: 44, 页码: 280-286
Authors:  Ma, Hong-Ying;  Yang, Jia-Da;  Hou, Jie;  Zou, Li-Wei;  Jin, Qiang;  Hao, Da-Cheng;  Ning, Jing;  Ge, Guang-Bo;  Yang, Ling
Favorite  |  View/Download:45/0  |  Submit date:2017/12/19
Ddab Hydrolysis  Carboxylesterase 2 (Ce2)  Species Differences  Liver Microsomes  
Comparative metabolism of DDAO benzoate in liver microsomes from various species 期刊论文
TOXICOLOGY IN VITRO, 2017, 卷号: 44, 页码: 280-286
Authors:  Ma, Hong-Ying;  Yang, Jia-Da;  Hou, Jie;  Zou, Li-Wei;  Jin, Qiang;  Hao, Da-Cheng;  Ning, Jing;  Ge, Guang-Bo;  Yang, Ling
Favorite  |  View/Download:57/0  |  Submit date:2017/12/19
Ddab Hydrolysis  Carboxylesterase 2 (Ce2)  Species Differences  Liver Microsomes  
Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention 期刊论文
NATURE MEDICINE, 2017, 卷号: 23, 页码: 859-+
Authors:  Liu, Ruixin;  Hong, Jie;  Xu, Xiaoqiang;  Feng, Qiang;  Zhang, Dongya;  Gu, Yanyun;  Shi, Juan;  Zhao, Shaoqian;  Liu, Wen;  Wang, Xiaokai;  Xia, Huihua;  Liu, Zhipeng;  Cui, Bin;  Liang, Peiwen;  Xi, Liuqing;  Jin, Jiabin;  Ying, Xiayang;  Wang, Xiaolin;  Zhao, Xinjie;  Li, Wanyu;  Jia, Huijue;  Lan, Zhou;  Li, Fengyu;  Wang, Rui;  Sun, Yingkai;  Yang, Minglan;  Shen, Yuxin;  Jie, Zhuye;  Li, Junhua;  Chen, Xiaomin;  Zhong, Huanzi;  Xie, Hailiang;  Zhang, Yifei;  Gu, Weiqiong;  Deng, Xiaxing;  Shen, Baiyong;  Xu, Xun;  Yang, Huanming;  Xu, Guowang;  Bi, Yufang;  Lai, Shenghan;  Wang, Jian;  Qi, Lu;  Madsen, Lise;  Wang, Jiqiu;  Ning, Guang;  Kristiansen, Karsten;  Wang, Weiqing
Favorite  |  View/Download:147/0  |  Submit date:2017/10/29