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Inhibition of human catechol-O-methyltransferase-mediated dopamine O-methylation by daphnetin and its Phase II metabolites 期刊论文
XENOBIOTICA, 2017, 卷号: 47, 期号: 6, 页码: 498-504
Authors:  Liang, Si-Cheng;  Ge, Guang-Bo;  Xia, Yang-Liu;  Dong, Pei-Pei;  Wang, Ping;  Qi, Xiao-Yi;  Tu, Cai-Xia;  Yang, Ling
Favorite  |  View/Download:28/0  |  Submit date:2017/10/29
Daphnetin  Comt Inhibitor  8-o-methyldaphnetin  Ligand-protein Interaction  Phase Ii Metabolite  Structural Modification  
Identifying and applying a highly selective probe to simultaneously determine the -glucuronidation activity of human UGT1A3 and UGT1A4 期刊论文
Scientific Reports, 2016, 卷号: 5, 期号: 0, 页码: 096271
Authors:  Li Jiang;  Liang SC(梁思成);  Chao Wang;  Ge GB(葛广波);  Xiao-Kui Huo;  Xiao-Yi Qi;  Sa Deng;  Ke-Xin Liu;  Xiao-Chi Ma
Favorite  |  View/Download:46/0  |  Submit date:2016/11/24
In Vitro Evaluation of the Effect of 7-Methyl Substitution on Glucuronidation of Daphnetin: Metabolic Stability, Isoform Selectivity, and Bioactivity Analysis 期刊论文
JOURNAL OF PHARMACEUTICAL SCIENCES, 2015, 卷号: 104, 期号: 10, 页码: 3557-3564
Authors:  Liang, Si-Cheng;  Ge, Guang-Bo;  Xia, Yang-Liu;  Zhang, Jiang-Wei;  Qi, Xiao-Yi;  Tu, Cai-Xia;  Yang, Ling
Favorite  |  View/Download:55/0  |  Submit date:2015/11/17
Daphnetin  Glucuronidation  Methyl Substitution  Structural Modification  Metabolic Stability  Phase Ii Enzymes  Glucuronosyltransferases  Human Liver Microsomes  Enzyme Kinetics  Metabolic Clearance  
LiAlH4/碳包覆金属纳米粒子(Ni-Co@C)复合储氢材料及其制备方法 专利
专利类型: 发明, 专利号: CN201210181590.3, 申请日期: 2015-06-10, 公开日期: 2015-06-10
Inventors:  孙立贤;  焦成丽;  张箭;  徐芬;  司晓亮;  赵梓名
Favorite  |  View/Download:59/0  |  Submit date:2015/11/16
Identifying and applying a highly selective probe to simultaneously determine the O-glucuronidation activity of human UGT1A3 and UGT1A4 期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5
Authors:  Jiang, Li;  Liang, Si-Cheng;  Wang, Chao;  Ge, Guang-Bo;  Huo, Xiao-Kui;  Qi, Xiao-Yi;  Deng, Sa;  Liu, Ke-Xin;  Ma, Xiao-Chi
Favorite  |  View/Download:45/0  |  Submit date:2015/11/17
Identification and Characterization of Human UDP-glucuronosyltransferases Responsible for the Glucuronidation of Fraxetin 期刊论文
DRUG METABOLISM AND PHARMACOKINETICS, 2014, 卷号: 29, 期号: 2, 页码: 135-140
Authors:  Xia, Yang-Liu;  Liang, Si-Cheng;  Zhu, Liang-Liang;  Ge, Guang-Bo;  He, Gui-Yuan;  Ning, Jing;  Lv, Xia;  Ma, Xiao-Chi;  Yang, Ling;  Yang, Sheng-Li;  Ge GB(葛广波)
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Fraxetin  Udp-glucuronosyltransferases (Ugts)  Ugt1a9  Glucuronidation  Human Liver Microsomes (Hlms)  
LiAlH4/碳包覆金属纳米粒子(Ni-Co@C)复合储氢材料及其制备方法 专利
专利类型: 发明, 专利号: CN201210181590.3, 申请日期: 2014-01-01, 公开日期: 2013-12-18
Inventors:  孙立贤;  焦成丽;  张箭;  徐芬;  司晓亮;  赵梓名
Favorite  |  View/Download:113/0  |  Submit date:2014/09/25
一种硼氮元素掺杂微孔碳材料的制备方法 专利
专利类型: 发明, 专利号: CN201210219781.4, 申请日期: 2014-01-01, 公开日期: 2014-01-15
Inventors:  孙立贤;  司晓亮;  徐芬;  张箭;  王自强
Favorite  |  View/Download:182/0  |  Submit date:2014/09/25
Heat capacities and thermodynamic properties of a 3D Cu(II) supramolecular complex 期刊论文
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, 2013, 卷号: 112, 期号: 3, 页码: 1565-1571
Authors:  Jiao, Cheng-Li;  Wang, Shuang;  Si, Xiao-Liang;  Li, Zhi-Bao;  Liu, Shuang;  Zhang, Jian;  Sun, Li-Xian;  Xu, Fen;  Sun, Yu-Jia;  Zhou, Huai-Ying;  Sawada, Yutaka;  Sun LX(孙立贤)
Adobe PDF(320Kb)  |  Favorite  |  View/Download:236/97  |  Submit date:2014/09/11
Copper  Molar Heat Capacity  Supramolecule  Tg  Tmdsc  
Inhibitory effects of sanguinarine on human liver cytochrome P450 enzymes 期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2013, 卷号: 56, 页码: 392-397
Authors:  Qi, Xiao-Yi;  Liang, Si-Cheng;  Ge, Guang-Bo;  Liu, Yong;  Dong, Pei-Pei;  Zhang, Jiang-Wei;  Wang, Ao-Xue;  Hou, Jie;  Zhu, Liang-Liang;  Yang, Ling;  Tu, Cai-Xia;  Yang L(杨凌);  Tu CX(涂彩霞)
Adobe PDF(725Kb)  |  Favorite  |  View/Download:223/85  |  Submit date:2014/09/11
Sanguinarine  Human Liver Microsomes  Cytochrome P450 Enzyme  Drug-drug Interaction  Time-dependent Inhibition