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Inhibition of human catechol-O-methyltransferase-mediated dopamine O-methylation by daphnetin and its Phase II metabolites 期刊论文
XENOBIOTICA, 2017, 卷号: 47, 期号: 6, 页码: 498-504
Authors:  Liang, Si-Cheng;  Ge, Guang-Bo;  Xia, Yang-Liu;  Dong, Pei-Pei;  Wang, Ping;  Qi, Xiao-Yi;  Tu, Cai-Xia;  Yang, Ling
Favorite  |  View/Download:32/0  |  Submit date:2017/10/29
Daphnetin  Comt Inhibitor  8-o-methyldaphnetin  Ligand-protein Interaction  Phase Ii Metabolite  Structural Modification  
In Vitro Evaluation of the Effect of 7-Methyl Substitution on Glucuronidation of Daphnetin: Metabolic Stability, Isoform Selectivity, and Bioactivity Analysis 期刊论文
JOURNAL OF PHARMACEUTICAL SCIENCES, 2015, 卷号: 104, 期号: 10, 页码: 3557-3564
Authors:  Liang, Si-Cheng;  Ge, Guang-Bo;  Xia, Yang-Liu;  Zhang, Jiang-Wei;  Qi, Xiao-Yi;  Tu, Cai-Xia;  Yang, Ling
Favorite  |  View/Download:61/0  |  Submit date:2015/11/17
Daphnetin  Glucuronidation  Methyl Substitution  Structural Modification  Metabolic Stability  Phase Ii Enzymes  Glucuronosyltransferases  Human Liver Microsomes  Enzyme Kinetics  Metabolic Clearance  
Inhibitory effects of sanguinarine on human liver cytochrome P450 enzymes 期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2013, 卷号: 56, 页码: 392-397
Authors:  Qi, Xiao-Yi;  Liang, Si-Cheng;  Ge, Guang-Bo;  Liu, Yong;  Dong, Pei-Pei;  Zhang, Jiang-Wei;  Wang, Ao-Xue;  Hou, Jie;  Zhu, Liang-Liang;  Yang, Ling;  Tu, Cai-Xia;  Yang L(杨凌);  Tu CX(涂彩霞)
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Sanguinarine  Human Liver Microsomes  Cytochrome P450 Enzyme  Drug-drug Interaction  Time-dependent Inhibition  
THE INHIBITORY EFFECT OF SANGUINARINE ON CYTOCHROME P450 ISOFORMS IN HUMAN LIVER 会议论文
19th Microsomes and Drug Oxidations /12th European International Society for the Study of Xenobiotics Meeting, 阿姆斯特丹, 2012-6-17
Authors:  Qi XY(齐晓怡);  Liang SC(梁思成);  Ge GB(葛广波);  Dong PP(董佩佩);  Zhang JW(张江伟);  Wang AX(王傲雪);  Tu CX(涂彩霞);  Yang L(杨凌)
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C5-Hydroxylation of liquiritigenin is catalyzed selectively by CYP1A2 期刊论文
XENOBIOTICA, 2011, 卷号: 41, 期号: 5, 页码: 349-357
Authors:  Wang, Ao-Xue;  Hu, Ying;  Liu, Hui-Xin;  Qi, Xiao-Yi;  Liu, Yong;  Tu, Cai-Xia;  Yang, Ling;  Hui-XinLiu
Adobe PDF(838Kb)  |  Favorite  |  View/Download:315/86  |  Submit date:2012/07/09
Liquiritigenin  Cytochrome P450  Human Liver Microsomes  Metabolism  
Rapid profiling and target analysis of principal components in Fuling Decoctions by UFLC-DAD-ESI-MS 期刊论文
FITOTERAPIA, 2010, 卷号: 81, 期号: 6, 页码: 662-667
Authors:  Wang, Ao-Xue;  Ge, Guang-Bo;  Qi, Xiao-Yi;  Hu, Ying;  Liang, Si-Cheng;  Yang, Ling;  Tu, Cai-Xia;  Tu CX
Favorite  |  View/Download:175/0  |  Submit date:2010/11/30
Uflc-dad-esi-ms  Fuling Decoction  Genipingentiobioside  Geniposide  Paeoniflorin  Liquiritin  
中药复方茯苓汤有效成分的初步研究 期刊论文
中国实验方剂学杂志, 2010, 卷号: 16, 期号: 11, 页码: 120-124
Authors:  王傲雪、葛广波、齐晓怡、胡莹、林玲、林茂、涂彩霞、杨凌;  涂彩霞
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干扰素γ/Fas介导的HaCaT细胞凋亡及8种人参皂甙的作用 期刊论文
中国皮肤性病学杂志, 2007, 卷号: 21, 期号: 10, 页码: 583-585
Authors:  刘影;  涂彩霞;  郝大程;  张蕴颖;  杨凌
Favorite  |  View/Download:125/0  |  Submit date:2010/11/30