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EGFR signaling confers resistance to BET inhibition in hepatocellular carcinoma through stabilizing oncogenic MYC 期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2019, 卷号: 38, 页码: 15
Authors:  Yin, Yalei;  Sun, Mingju;  Zhan, Xi;  Wu, Changqing;  Geng, Pengyu;  Sun, Xiaoyan;  Wu, Yunsong;  Zhang, Shuijun;  Qin, Jianhua;  Zhuang, Zhengping;  Liu, Yang
Favorite  |  View/Download:6/0  |  Submit date:2019/06/20
Bromodomain  JQ1  MAPK pathway  MYC  EGFR mutation  Sorafenib  
Label-free cell phenotypic study of FFA4 and FFA1 and discovery of novel agonists of FFA4 from natural products 期刊论文
RSC ADVANCES, 2019, 卷号: 9, 期号: 26, 页码: 15073-15083
Authors:  Xu, Fangfang;  Zhou, Han;  Liu, Xiumei;  Zhang, Xiuli;  Wang, Zhiwei;  Hou, Tao;  Wang, Jixia;  Qu, Lala;  Zhang, Pengyu;  Piao, Hailong;  Liang, Xinmiao
Favorite  |  View/Download:1/0  |  Submit date:2019/07/26
Discovery of novel antagonists on (2)-adrenoceptor from natural products using a label-free cell phenotypic assay 期刊论文
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2018, 卷号: 391, 期号: 12, 页码: 1411-1420
Authors:  Zhang, Pengyu;  Wang, Jixia;  Zhao, Ying;  Zhang, Xiuli;  Qu, Lala;  Wang, Chaoran;  Feng, Jiatao;  Wang, Anhui;  Zhou, Weijia;  Liu, Yanfang;  Hou, Tao;  Zhou, Han;  Wang, Zhiwei;  Liang, Xinmiao
Favorite  |  View/Download:10/0  |  Submit date:2019/06/20
beta(2)-Adrenoceptor  Antagonist  Natural product  Label-free cell phenotypic assay  
Discovery of beta(2)-adrenoceptor agonists in Curcuma zedoaria Rosc using label-free cell phenotypic assay combined with two-dimensional liquid chromatography 期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2018, 卷号: 1577, 页码: 59-65
Authors:  Zhou, Weijia;  Wang, Jixia;  Zhao, Yaopeng;  Yu, Long;  Fang, Ye;  Jin, Hongli;  Zhou, Han;  Zhang, Pengyu;  Liu, Yanfang;  Zhang, Xiuli;  Liang, Xinmiao
Favorite  |  View/Download:7/0  |  Submit date:2019/06/20
Curcuma zedoaria Rosc  beta(2)-adrenoceptor agonists  Diarylheptanoids  Label-free cell phenotypic assay  Two-dimensional liquid chromatography  
Direct Reprogramming of Human Fibroblasts to Functional and Expandable Hepatocytes 期刊论文
CELL STEM CELL, 2014, 卷号: 14, 期号: 3, 页码: 370-384
Authors:  Huang, Pengyu;  Zhang, Ludi;  Gao, Yimeng;  He, Zhiying;  Yao, Dan;  Wu, Zhitao;  Cen, Jin;  Chen, Xiaotao;  Liu, Changcheng;  Hu, Yiping;  Lai, Dongmei;  Hu, Zhenlei;  Chen, Li;  Zhang, Ying;  Cheng, Xin;  Ma, Xiaojun;  Pan, Guoyu;  Wang, Xin;  Hui, Lijian;  LijianHui
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Anisotropic Coarse-Grained Model for Proteins Based On Gay-Berne and Electric Multipole Potentials 期刊论文
JOURNAL OF CHEMICAL THEORY AND COMPUTATION, 2014, 卷号: 10, 期号: 2, 页码: 731-750
Authors:  Shen, Hujun;  Li, Yan;  Ren, Pengyu;  Zhang, Dinglin;  Li, Guohui;  Li GH(李国辉)
Adobe PDF(3842Kb)  |  Favorite  |  View/Download:35/14  |  Submit date:2015/11/16
Role of Bivalent Cations in Structural Stabilities of New Drug Targets-Vaccinia-related Kinases (VRK) from Molecular Dynamics Simulations 期刊论文
CURRENT PHARMACEUTICAL DESIGN, 2013, 卷号: 19, 期号: 12, 页码: 2269-2281
Authors:  Fu, Ting;  Ren, Hong;  Zhang, Jiajing;  Ren, Pengyu;  Enyedy, Istvan;  Li, Guohui
Favorite  |  View/Download:12/0  |  Submit date:2015/11/09
Pseudokinases  Vaccinia Related Kinase  Bivalent Cations  Structural Stabilities  Molecular Dynamics Simulations  
Role of Bivalent Cations in Structural Stabilities of New Drug Targets ——Vaccinia-related Kinases (VRK) from Molecular Dynamics Simulations 期刊论文
Current Pharmaceutical Design, 2013, 卷号: 19, 页码: 2269
Authors:  付婷;  Hong Ren;  Jiajing Zhang;  Pengyu Ren;  Istvan Enyedy;  李国辉
Adobe PDF(703Kb)  |  Favorite  |  View/Download:110/48  |  Submit date:2014/09/11
Study on Conformation Interconversion of 3-Alkyl-4-acetyl-3;4-dihydro-2H-1;4-benzoxazines from Dynamic NMR Experiments and ab Initio Density Functional Calculations 期刊论文
Journal of Physical Chemistry B, 2005, 卷号: 109, 页码: 18690-18698
Authors:  Yang G(杨刚);  Han XW(韩秀文);  Zhang WP(张维萍);  Liu XM(刘秀梅);  Yang PY(杨鹏宇);  Zhou YG(周永贵);  Bao XH(包信和);  Yang G(杨刚);  Han XW(韩秀文);  Zhang WP(张维萍);  Liu XM(刘秀梅);  Yang PY(杨鹏宇);  Zhou YG(周永贵);  Bao XH(包信和)
Adobe PDF(435Kb)  |  Favorite  |  View/Download:186/66  |  Submit date:2010/11/30